Pharmacological properties of chalcones: a review of preclinical including molecular mechanisms and clinical evidence

B Salehi, C Quispe, I Chamkhi, N El Omari… - Frontiers in …, 2021 - frontiersin.org
Chalcones are among the leading bioactive flavonoids with a therapeutic potential
implicated to an array of bioactivities investigated by a series of preclinical and clinical …

[HTML][HTML] Murraya koenigii (L.) Spreng: speculative ethnobotanical perspectives of ubiquitous herb with versatile nutra/functional properties

P Suthar, S Kumar, V Kumar, D Vaidya… - South African Journal of …, 2022 - Elsevier
The utilization of various herbals in the different traditional therapeutical and medicinal
systems has been reported prehistorically. India due to its geographical positioning on the …

[PDF][PDF] Dried flower powder combination of Clitoria ternatea and Punica granatum demonstrated analogous anti-hyperglycemic potential as compared with standard …

SP Borikar, NG Kallewar, DK Mahapatra… - Journal of applied …, 2018 - japsonline.com
The diabetes mellitus type-2 (DMT-2) is among the highly escalating disease that is
expected to affect nearly 400 million people across the globe by the end of 2030. In DMT-2 …

Murrayanine-chalcone transformed into novel pyrimidine compounds demonstrated promising anti-inflammatory activity

DK Mahapatra, RS Shivhare… - Asian Journal of …, 2018 - indianjournals.com
A new series of murrayanine based pyrimidine derivatives were synthesized from the
previously reported starting material, known as murrayanine-chalcone and urea as the …

Structural, spectroscopic and quantum chemical analysis of an exocyclic extended double-bonded chalcone single crystal, with pharmaceutical scanning for breast …

MK Priya, DR Jonathan, S Muthu, FB Asif… - Journal of Molecular …, 2022 - Elsevier
Abstract A chalcone derivative,(2E)-2-[(2E)-3-(4-methoxyphenyl) prop‑2-en-1-ylidene]-3, 4-
dihydronaphthalen-1 (2H)-one [MPDN] was synthesized by slow evaporation method using …

Anxiolytic activity of some 2, 3-dihydrobenzo [b][1, 4] oxazepine derivatives synthesized from Murrayanine-Chalcone

DK Mahapatra, RS Shivhare… - Asian Journal of …, 2018 - indianjournals.com
Due to the fact that, Murrayanine is one of the most active compounds of the present
carbazole series with a simple chemistry which facilitate multiple sites for substituting varied …

[PDF][PDF] Design and formulating gliclazide solid dispersion immediate release layer and metformin sustained release layer in bilayer tablet for the effective postprandial …

PS Gangane, MM Kadam, DK Mahapatra… - Int J Pharm Sci …, 2018 - researchgate.net
In order to effectively manage the diabetic mellitus type-II hyperglycemic surge, bilayered
tablets comprising of gliclazide in immediate release layer (IRL) and metformin in sustained …

Synthesis and chemical exploration of an organic exocyclic chalcone derivative for its therapeutic proficiency against breast cancer

M Krishna Priya, D Reuben Jonathan… - Polycyclic Aromatic …, 2022 - Taylor & Francis
Abstract (2E)-2-(3-(benzyloxy)-4-methoxybenzylidene)-3, 4-dihydronaphthalen-1 (2H)-one
[BMBD] was synthesized to obtain a single crystal. Single crystal X-ray Diffraction (SXRD) …

Anti-inflammatory potentials of some novel Murrayanine containing 1, 3, 4-Oxadiazole derivatives

DK Mahapatra, RS Shivhare… - Asian Journal of …, 2018 - indianjournals.com
Based on the assumption that designing compounds with all the three features; a natural
product, a synthetic component, and a functional Schiff's base will surely lead to the …

[PDF][PDF] Murrayanine-hydantoin and-thiohydantoin analogs as promising anti-convulsant agents: Synthesis, Characterization and Molecular Docking Studies

DK Mahapatra, D Das, RS Shivhare - MOJ Biorg Org Chem, 2018 - academia.edu
Epilepsy is the oldest neurological disease of the brain characterized by hypersynchronous
neuronal firing and hyperexcitability that finds recognition in ancient medical texts, dated …