Anticancer potential of andrographolide from Andrographis paniculata (Burm. f.) Nees and its mechanisms of action

Z Malik, R Parveen, B Parveen, S Zahiruddin… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Synthetic drugs used for cancer treatment have side
effects that may be immunosupressive, can cause liver, kidney and cardiac toxicity, and …

Advances on natural abietane, labdane and clerodane diterpenes as anti-cancer agents: Sources and mechanisms of action

R Acquaviva, GA Malfa, MR Loizzo, J Xiao, S Bianchi… - Molecules, 2022 - mdpi.com
Extensive research over the past decades has identified numerous phytochemicals that
could represent an important source of anti-cancer compounds. There is an immediate need …

[HTML][HTML] The anti-cancer effect of flaxseed lignan derivatives on different acute myeloid leukemia cancer cells

S Tannous, T Haykal, J Dhaini, MH Hodroj… - Biomedicine & …, 2020 - Elsevier
Flaxseeds have been known for their anti-cancerous effects due to the high abundance of
lignans released upon ingestion. The most abundant lignan, secoisolariciresinol diglucoside …

Enhanced anti-cancer activity of andrographis with oligomeric proanthocyanidins through activation of metabolic and ferroptosis pathways in colorectal cancer

T Shimura, P Sharma, GG Sharma, JK Banwait… - Scientific Reports, 2021 - nature.com
The high degree of morbidity and mortality in colorectal cancer (CRC) patients is largely due
to the development of chemoresistance against conventional chemotherapeutic drugs. In …

Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells

T Haykal, P Nasr, MH Hodroj, RI Taleb, R Sarkis… - Toxins, 2019 - mdpi.com
Annona cherimola Mill is a large green fruit with black seeds widely known to possess toxic
properties due to the presence of Annonaceous acetogenins. The present study investigates …

Thymoquinone-chemotherapeutic combinations: new regimen to combat cancer and cancer stem cells

AH El-Far, MA Tantawy, SK Al Jaouni… - … Archives of Pharmacology, 2020 - Springer
Cancer is a worldwide disease that causes millions of cases of mortality and morbidity. The
major problem associated with the cancer is its resistance to conventional therapy and a …

In vivo and in vitro anti-inflammatory activity evaluation of Lebanese Cannabis sativa L. ssp. indica (Lam.)

W Shebaby, J Saliba, WH Faour, J Ismail… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Cannabis sativa L. is an aromatic annual herb belonging
to the family Cannabaceae and it is widely distributed worldwide. Cultivation, selling, and …

Beta-tocotrienol exhibits more cytotoxic effects than gamma-tocotrienol on breast cancer cells by promoting apoptosis via a P53-independent PI3-kinase dependent …

M Idriss, MH Hodroj, R Fakhoury, S Rizk - Biomolecules, 2020 - mdpi.com
Studies on tocotrienols have progressively revealed the benefits of these vitamin E isoforms
on human health. Beta-tocotrienol (beta-T3) is known to be less available in nature …

The pro-apoptotic effect of a Terpene-rich Annona cherimola leaf extract on leukemic cell lines

C Ammoury, M Younes, M El Khoury… - … and alternative medicine, 2019 - Springer
Abstract Background The edible fruit Annona cherimola has previously shown many
nutritional and medicinal properties. The current study evaluates the anti-cancer and anti …

Drug-Herb Interactions among Thai Herbs and Anticancer Drugs: A Scoping Review

A Jiso, P Khemawoot, P Techapichetvanich… - Pharmaceuticals, 2022 - mdpi.com
More than half of Thai patients with cancer take herbal preparations while receiving
anticancer therapy. There is no systematic or scoping review on interactions between …