Does childhood adversity alter opioid drug reward? A conceptual replication in outpatients before surgery

M Carlyle, M Kvande, IM Meier… - Addiction Research & …, 2024 - Taylor & Francis
Introduction Opioid analgesic treatment during surgery entails the risk of persistent use.
Experiences of childhood adversity have been shown to increase opioid reward in …

[HTML][HTML] Opioid Regulation of Social Homeostasis: Connecting Loneliness to Addiction

G Løseth, M Eikemo, S Leknes - Biological Psychiatry, 2024 - Elsevier
Loneliness heightens the risk of substance use disorder, and a desire to escape this
negative feeling motivates drug use. Opioid drugs in particular are believed to target …

Factors associated with use of opioid rescue medication after surgery

IM Meier, M Eikemo, M Trøstheim, K Buen… - Regional Anesthesia & …, 2024 - rapm.bmj.com
Background Opioid exposure after surgery increases risk of persistent opioid use. Here, we
characterize at-home use of opioid rescue medication during 1–2 days after outpatient …

Aktuelle Herausforderungen in der Behandlung der Opioidabhängigkeit

A Heinz, S Gutwinski, M Krausz, G Ernst, M Vogel… - Der Nervenarzt, 2024 - Springer
Zusammenfassung Hintergrund Die Zahl opioidkonsumierender Personen ist weltweit seit
mehr als einem Jahrzehnt ansteigend, insbesondere der Konsum von Opioidanalgetika in …

Stress-enhanced opioid self-administration in healthy men: A randomized controlled experimental medicine study

Men are disproportionately likely to develop opioid use disorder, yet the mechanisms of
addiction risk in men and women remain poorly understood. Preclinical, epidemiological …

[PDF][PDF] Does childhood adversity alter opioid drug reward? A conceptual replication in outpatients before surgery

M Kvande, M Carlyle, S Leknes, I Meier, M Trøstheim… - rr.peercommunityin.org
Experiences of childhood adversity has been shown to increase opioid reward in preclinical
models, and wasa finding recently extended to healthy humans. We tested whether …

Intraoperative pain management: Regarding intraoperative pain management, all patients received a Target Controlled Infusion (TCI) of Propofol (Schneiders model …

IM Meier - rapm.bmj.com
Methods Inclusion and exclusion criteria The participants recruited for the study were adult
patients healthy enough to undergo minor day surgery, classified as ASA-I-II defined in line …