Multi-wavelength analytical ultracentrifugation (MW-AUC) is a recent development made
possible by new analytical ultracentrifuge optical systems. MW-AUC extends the basic …

An essential step in bacterial transformation is the uptake of DNA into the periplasm, across
the thick peptidoglycan cell wall of Gram-positive bacteria, or the outer membrane and thin …

Transcription is the principal control point for bacterial gene expression, and it enables a
global cellular response to an intracellular or environmental trigger. Transcriptional …

Lipid nanoparticles as delivery system for mRNA have recently attracted attention to a
broader audience as COVID-19 mRNA vaccines. Their low immunogenicity and capability to …

Aim: We present multi-wavelength (MW) analytical ultracentrifugation (AUC) methods
offering superior accuracy for adeno-associated virus characterization and quantification …

Bacteria respond to environmental changes by inducing transcription of some genes and
repressing others. Sialic acids, which coat human cell surfaces, are a nutrient source for …

Due to the rise of adeno-associated viruses (AAVs) as gene therapy delivery vectors,
boundary sedimentation velocity analytical ultracentrifugation (boundary SV-AUC) has been …

Analytical ultracentrifugation experiments play an integral role in the solution‐phase
characterization of biological macromolecules and their interactions. This unit discusses the …

There are five known general catalytic mechanisms used by enzymes to catalyze
carbohydrate epimerization. The amino sugar epimerase N-acetylmannosamine-6 …

Understanding the nature of macromolecules and their interactions in solution underpins
many fields, including biology, chemistry and materials science. The 24th International …