Frailty is intertwined with heart failure: mechanisms, prevalence, prognosis, assessment, and management

A Pandey, D Kitzman, G Reeves - JACC: Heart Failure, 2019 - jacc.org
Frailty, a syndrome characterized by an exaggerated decline in function and reserve of
multiple physiological systems, is common in older patients with heart failure (HF) and is …

[HTML][HTML] COVID-19-associated cardiovascular morbidity in older adults: a position paper from the Italian Society of Cardiovascular Researches

F Moccia, A Gerbino, V Lionetti, M Miragoli… - Geroscience, 2020 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells following
binding with the cell surface ACE2 receptors, thereby leading to coronavirus disease 2019 …

Inflammaging as a common ground for the development and maintenance of sarcopenia, obesity, cardiomyopathy and dysbiosis

G Livshits, A Kalinkovich - Ageing research reviews, 2019 - Elsevier
Sarcopenia, obesity and their coexistence, obese sarcopenia (OBSP) as well as
atherosclerosis-related cardio-vascular diseases (ACVDs), including chronic heart failure …

Immune system and sarcopenia: Presented relationship and future perspective

X Zhang, H Li, M He, J Wang, Y Wu, Y Li - Experimental Gerontology, 2022 - Elsevier
Sarcopenia, a geriatric syndrome that is characterized by a progressive and generalized
skeletal muscle disorder, can be associated with many comorbidities, including obesity …

Older adults in the cardiac intensive care unit: factoring geriatric syndromes in the management, prognosis, and process of care: a scientific statement from the …

AA Damluji, DE Forman, S Van Diepen, KP Alexander… - Circulation, 2020 - Am Heart Assoc
Longevity is increasing, and more adults are living to the stage of life when age-related
biological factors determine a higher likelihood of cardiovascular disease in a distinctive …

The role of toll‐like receptor signaling in the progression of heart failure

L Yu, Z Feng - Mediators of inflammation, 2018 - Wiley Online Library
Medical systems worldwide are being faced with a growing need to understand mechanisms
behind the pathogenesis of heart failure (HF) that is considered as a leading cause of …

[HTML][HTML] Redefining the perioperative stress response: a narrative review

V Manou-Stathopoulou, M Korbonits… - British journal of …, 2019 - Elsevier
The systemic stress response triggered by surgical trauma is characterised by sterile
inflammation preceding metabolic and neuroendocrine dysregulation. However, the …

Frailty and the risk of all‐cause mortality and hospitalization in chronic heart failure: a meta‐analysis

I Uchmanowicz, CS Lee, C Vitale, S Manulik… - ESC heart …, 2020 - Wiley Online Library
To estimate the risk of all‐cause mortality and hospitalization in frail patients with chronic
heart failure (HF), a systematic search and meta‐analysis was carried out to identify all …

The impact of frailty on mortality after heart transplantation

PS Macdonald, N Gorrie, X Brennan, SR Aili… - The Journal of Heart and …, 2021 - Elsevier
BACKGROUND Frailty is prevalent in the patients with advanced heart failure; however, its
impact on clinical outcomes after heart transplantation (HTx) is unclear. The aim of this study …

Emerging cross-talks between chronic kidney disease–mineral and bone disorder (CKD–MBD) and malnutrition–inflammation complex syndrome (MICS) in patients …

S Yamada, K Tsuruya, T Kitazono, T Nakano - Clinical and Experimental …, 2022 - Springer
Chronic kidney disease–mineral and bone disorder (CKD–MBD) is a systemic disorder that
affects multiple organs and systems and increases the risk of morbidity and mortality in …