In 2007, the world solemnized the golden jubilee of the discovery of interferon (IFN).
Interferon is a small protein messenger called a pluripotent cytokine, produced by several …

Selection plays a major role in the determination of codon usage in all organisms studied so
far. In highly expressed genes, a narrow set of codons is used and these codons correspond …

Overexpression of rhIFN-α2b was obtained by synthesizing a codon optimized gene for IFN-
α2b and expressing it in the form of inclusion bodies (IBs) in Escherichia coli. The …

US8119603B2 - Modified human interferon polypeptides and their uses - Google Patents
US8119603B2 - Modified human interferon polypeptides and their uses - Google Patents …

In Escherichia coli (E. coli), a low-usage codon is defined as a codon that is used rarely or
infrequently in the genome with usage frequency lower than the smallest value (or frequency …

Background Kuruma shrimp, a major commercial shrimp species in the world, has two
cryptic or sibling species, Marsupenaeus japonicus and Marsupenaeus pulchricaudatus …

Although more and more entangled participants of translation process were realized, how
they cooperate and co-determine the final translation efficiency still lacks details. Here, we …

US8097702B2 - Modified human interferon polypeptides with at least one non-naturally
encoded amino acid and their uses - Google Patents US8097702B2 - Modified human …

In species having a strong correlation of expressivity and codon bias it has been shown that
heterologous expression can be optimized by changing codons of the introduced gene …

Exogenous transfer RNAs (tRNAs) favor translation of bovine papillomavirus 1 wild-type (wt)
L1 mRNA in in vitro translation systems (Zhou et al. 1999, J. Virol., 73, 4972–4982). We …