A large number of pharmacological studies have used capsaicin as a tool to activate many
physiological systems, with an emphasis on pain research but also including functions such …

Clinical studies comparing the response and side effects of various opioids have not been
able to show robust differences between drugs. Hence, recommendations of the regulatory …

Pain models in animals have shown low predictivity for analgesic efficacy in humans, and
clinical studies are often very confounded, blurring the evaluation. Human experimental pain …

Rationale Over the last decade, oxycodone has become one of the most widely abused
drugs in the USA. Oxycodone use disorder (OUD) is a serious health problem that has …

Visceral pain is experienced by 40% of the population, and 28% of cancer patients suffer
from pain arising from intra‐abdominal metastasis or from treatment. Neuroanatomy of …

Modulation of pain may result from engagement of opioid receptors in multiple brain regions.
Whether sensory and affective qualities of pain are differentially affected by brain opioid …

Introduction Optimal pain management is crucial to the postoperative recovery process. We
aimed to evaluate the efficacy and safety of intravenous oxycodone with intravenous …

This paper is a summary of presentations on postoperative pain control by the authors at the
2014 PainForum meeting in People's Republic of China. Postoperative pain is often …

1.1 Aim This guideline plays an important role in the process of consolidation and
improvement of care for patients with abdominal and pelvic pain. From both literature and …

Background Impaired pain inhibitory and enhanced pain facilitatory mechanisms are
repeatedly reported in patients with central sensitization pain. However, the exact effects of …