Neurodegenerative diseases are debilitating disorders that feature progressive and
selective loss of function or structure of anatomically or physiologically associated neuronal …

Clinical specialization is not only a force for progress, but it has also led to the fragmentation
of medical knowledge. The focus of research in the field of Alzheimer's disease (AD) is …

In the rapidly moving proteomics field, a diverse patchwork of data analysis pipelines and
algorithms for data normalization and differential expression analysis is used by the …

Hereditary ATTR (ATTRm) amyloidosis (also called transthyretin-type familial amyloid
polyneuropathy [ATTR-FAP]) is an autosomal-dominant, adult-onset, rare systemic disorder …

Microglia are the resident immune cells of the central nervous system that guarantee
immune surveillance and exert also a modulating role on neuronal synaptic development …

Transthyretin (TTR) is a tetrameric protein transporting hormones in the plasma and brain,
which has many other activities that have not been fully acknowledged. TTR is a positive …

Alzheimer's disease (AD) represents a progressive amyloidogenic disorder whose
advancement is widely recognized to be connected to amyloid-β peptides and Tau …

Transthyretin (TTR), an homotetrameric protein mainly synthesized by the liver and the
choroid plexus, and secreted into the blood and the cerebrospinal fluid, respectively, has …

This review examines the role of impaired amyloid-β clearance in the accumulation of
amyloid-β in the brain and the periphery, which is closely associated with Alzheimer's …

Mild traumatic brain injury (mTBI) results in broad neurological symptoms and an increased
risk of being diagnosed with a neurodegenerative disease later in life. While the immediate …