Over the past decade the number and variety of protein post-translational modifications that
have been detected and characterized in bacteria have rapidly increased. Most post …

Two-component systems (TCS) comprising sensor histidine kinases and response regulator
proteins are among the most important players in bacterial and archaeal signal transduction …

Limits and barriers to adaptation restrict people's ability to address the negative impacts of
climate change or manage risks in a way that maximises their wellbeing. There is a lack of …

Bacteria possess a repertoire of versatile protein kinases modulating diverse aspects of their
physiology by phosphorylating proteins on various amino acids including histidine, cysteine …

Bacterial cells are encased in a peptidoglycan (PG) exoskeleton that protects them from
osmotic lysis and specifies their distinct shapes. Cell wall hydrolases are required to enlarge …

Protein modifications not only affect protein homeostasis but can also establish new cellular
protein functions and are important components of complex cellular signal sensing and …

The main family of serine/threonine/tyrosine protein kinases present in eukarya was defined
and described by Hanks et al. in 1988 (Science, 241, 42–52). It was initially believed that …

Palaeontologically, eubacteria are> 3× older than neomura (eukaryotes, archaebacteria).
Cell biology contrasts ancestral eubacterial murein peptidoglycan walls and derived …

Among the 16 two-component systems in the opportunistic human pathogen
Staphylococcus aureus, only WalKR is essential. Like the orthologous systems in other …

The assembly of the bacterial cell wall requires synchronization of a multitude of biosynthetic
machineries and regulatory networks. The eukaryotic-like serine/threonine kinase PknB has …