Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs)
are widely expressed and have key roles in gene regulation. Recent studies have begun to …

While there exist some long non-coding RNAs (lncRNAs) that are structurally similar to
mRNAs (capped, spliced, poly a tail), not all of the lncRNAs exhibit these features …

Long noncoding RNAs (lncRNAs) are emerging as critical regulators of gene expression in
the immune system. Studies have shown that lncRNAs are expressed in a highly lineage …

Long non-coding RNAs (lncRNAs) are a class of noncoding RNAs with a length larger than
200 nucleotides that participate in various diseases and biological processes as they can …

It is estimated that more than 90% of the mammalian genome is transcribed as non-coding
RNAs. Recent evidences have established that these non-coding transcripts are not junk or …

Neutrophils, eosinophils and 'classical'monocytes collectively account for about 70% of
human blood leukocytes and are among the shortest-lived cells in the body,. Precise …

High throughput single-cell RNA-seq has been successfully implemented to dissect the
cellular and molecular features underlying hematopoiesis. However, an elaborate and …

People with type 2 diabetes mellitus (T2DM) have a 25-fold higher risk of limb loss than non-
diabetics due in large part to impaired wound healing. Here, we show that the impaired …

Hematopoietic stem cells differentiate into a broad range of specialized blood cells. This
process is tightly regulated and depends on transcription factors, micro-RNAs, and long non …

Long noncoding RNAs (lncRNAs) are increasingly recognized as vital components of gene
programs controlling cell differentiation and function. Central to their functions is an ability to …