[HTML][HTML] Bottom-up proteomics: advancements in sample preparation
Liquid chromatography–tandem mass spectrometry (LC–MS/MS)-based proteomics is a
powerful technique for profiling proteomes of cells, tissues, and body fluids. Typical bottom …
powerful technique for profiling proteomes of cells, tissues, and body fluids. Typical bottom …
[HTML][HTML] Biomarkers in neurodegenerative diseases: proteomics spotlight on ALS and Parkinson's disease
R Raghunathan, K Turajane, LC Wong - International Journal of …, 2022 - mdpi.com
Neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson's
disease (PD) are both characterized by pathogenic protein aggregates that correlate with …
disease (PD) are both characterized by pathogenic protein aggregates that correlate with …
[HTML][HTML] Evaluation and refinement of sample preparation methods for extracellular matrix proteome coverage
The extracellular matrix is a key component of tissues, yet it is underrepresented in
proteomic datasets. Identification and evaluation of proteins in the extracellular matrix (ECM) …
proteomic datasets. Identification and evaluation of proteins in the extracellular matrix (ECM) …
Multiplexed imaging mass spectrometry of the extracellular matrix using serial enzyme digests from formalin-fixed paraffin-embedded tissue sections
We report a multiplexed imaging mass spectrometry method which spatially localizes and
selectively accesses the extracellular matrix on formalin-fixed paraffin-embedded tissue …
selectively accesses the extracellular matrix on formalin-fixed paraffin-embedded tissue …
[HTML][HTML] A glycomics and proteomics study of aging and Parkinson's disease in human brain
Previous studies on Parkinson's disease mechanisms have shown dysregulated
extracellular transport of α-synuclein and growth factors in the extracellular space. In the …
extracellular transport of α-synuclein and growth factors in the extracellular space. In the …
[HTML][HTML] In-depth matrisome and glycoproteomic analysis of human brain glioblastoma versus control tissue
Glioblastoma (GBM) is the most common and malignant primary brain tumor. The
extracellular matrix, also known as the matrisome, helps determine glioma invasion …
extracellular matrix, also known as the matrisome, helps determine glioma invasion …
[HTML][HTML] Proteomics in forensic analysis: Applications for human samples
Proteomics, the large-scale study of all proteins of an organism or system, is a powerful tool
for studying biological systems. It can provide a holistic view of the physiological and …
for studying biological systems. It can provide a holistic view of the physiological and …
Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020
DJ Harvey - Mass Spectrometry Reviews, 2023 - Wiley Online Library
This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …
Matrisome changes in Parkinson's disease
Extracellular matrix (ECM) proteins, collectively known as the matrisome, include collagens,
glycoproteins, and proteoglycans. Alterations in the matrisome have been implicated in the …
glycoproteins, and proteoglycans. Alterations in the matrisome have been implicated in the …
Advances in the proteomic profiling of the matrisome and adhesome
Introduction The matrisome and adhesome comprise proteins that are found within or are
associated with the extracellular matrix (ECM) and adhesion complexes, respectively …
associated with the extracellular matrix (ECM) and adhesion complexes, respectively …