Acute decompensation (AD) of cirrhosis is defined by the development of ascites, hepatic
encephalopathy (HE) and/or variceal bleeding. Ascites is traditionally attributed to …

The definition of acute-on-chronic liver failure (ACLF) remains contested. In Europe and
North America, the term is generally applied according to the European Association for the …

Acute-on-chronic liver failure (ACLF) is a recently recognized syndrome characterized by
acute decompensation (AD) of cirrhosis and organ/system failure (s)(organ failure: liver …

Acute-on-chronic liver failure (ACLF) is an increasingly recognised entity encompassing an
acute deterioration of liver function in patients with cirrhosis, which is usually associated with …

Portal hypertension is a severe and frequent complication of chronic liver disease. Its
consequences, bleeding from gastroesophageal varices and portal hypertensive …

Steatosis of the liver may arise from a variety of conditions, but the molecular basis for lipid
droplet formation is poorly understood. Although a certain amount of lipid storage may even …

More than several hundreds of millions of people will be diabetic and obese over the next
decades in front of which the actual therapeutic approaches aim at treating the …

A “leaky gut” may be the cutting edge for the passage of toxins, antigens or bacteria into the
body, and may play a pathogenic role in advanced liver cirrhosis and its complications …

Portal hypertension is caused by an increased intrahepatic resistance, a major
consequence of cirrhosis. Endothelial dysfunction in liver sinusoidal endothelial cells …

Hepatic fibrosis : Current Opinion in Gastroenterology Hepatic fibrosis : Current Opinion in
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