Acute renal failure and sepsis

RW Schrier, W Wang - New England Journal of Medicine, 2004 - Mass Medical Soc
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[图书][B] Oxidation and antioxidants in organic chemistry and biology

ET Denisov, IB Afanas' ev - 2005 - taylorfrancis.com
Providing a comprehensive review of reactions of oxidation for different classes of organic
compounds and polymers, and biological processes mediated by free radicals, Oxidation …

Molybdenum-based nanoclusters act as antioxidants and ameliorate acute kidney injury in mice

D Ni, D Jiang, CJ Kutyreff, J Lai, Y Yan… - Nature …, 2018 - nature.com
Acute kidney injury (AKI) is a common reactive oxygen species (ROS)-related renal disease
that causes numerous deaths annually, yet only supportive treatment is currently available in …

Animal models of sepsis and sepsis-induced kidney injury

K Doi, A Leelahavanichkul, PST Yuen… - The Journal of clinical …, 2009 - Am Soc Clin Investig
Sepsis is characterized by a severe inflammatory response to infection, and its
complications, including acute kidney injury, can be fatal. Animal models that correctly mimic …

Acute renal failure: definitions, diagnosis, pathogenesis, and therapy

RW Schrier, W Wang, B Poole… - The Journal of clinical …, 2004 - Am Soc Clin Investig
Acute renal failure (ARF), characterized by sudden loss of the ability of the kidneys to
excrete wastes, concentrate urine, conserve electrolytes, and maintain fluid balance, is a …

Mediators of inflammation in acute kidney injury

A Akcay, Q Nguyen, CL Edelstein - Mediators of inflammation, 2009 - Wiley Online Library
Acute kidney injury (AKI) remains to be an independent risk factor for mortality and morbidity.
Inflammation is now believed to play a major role in the pathopathophysiology of AKI. It is …

Effects of tempol and redox-cycling nitroxides in models of oxidative stress

CS Wilcox - Pharmacology & therapeutics, 2010 - Elsevier
Tempol is a redox-cycling nitroxide that promotes the metabolism of many reactive oxygen
species (ROS) and improves nitric oxide bioavailability. It has been studied extensively in …

Immune cells: free radicals and antioxidants in sepsis

VM Victor, M Rocha, M De la Fuente - International immunopharmacology, 2004 - Elsevier
The excessive production of reactive oxygen species (ROS), associated with inflammation,
leads to a condition of oxidative stress. Oxidative stress is a major contributing factor to the …

Serial determination of glomerular filtration rate in conscious mice using FITC-inulin clearance

Z Qi, I Whitt, A Mehta, J Jin, M Zhao… - American Journal …, 2004 - journals.physiology.org
Two nonradioactive methods for determining glomerular filtration rate (GFR) in conscious
mice using FITC-labeled inulin (FITC-inulin) were evaluated. The first method measured …

Catalase and glutathione peroxidase mimics

BJ Day - Biochemical pharmacology, 2009 - Elsevier
Overproduction of the reactive oxygen species (ROS) superoxide (O2−) and hydrogen
peroxide (H2O2) are increasingly implicated in human disease and aging. ROS are also …