Forming the inner layer of the vascular system, endothelial cells (ECs) facilitate a multitude
of crucial physiological processes throughout the body. Vascular ECs enable the vessel wall …

Mucins are the main structural components of mucus that create a selective protective
barrier for epithelial surface and also execute wide range of other physiological functions …

Endothelial to mesenchymal transition (EndMT) plays a major role during development, and
also contributes to several adult cardiovascular diseases. Importantly, mesenchymal cells …

Mucus provides protective functions in the gastrointestinal tract and plays an important role
in the adhesion of microorganisms to host surfaces. Mucin glycoproteins polymerize, forming …

Cardiac fibrosis is characterized by excessive extracellular matrix deposition that contributes
to compromised cardiac function and potentially heart failure. Cardiac pressure overload …

It is now accepted that the growth of solid tumours is dependent on their capacity to acquire
a blood supply, and much effort has been directed towards the development of agents …

Schlemm's canal (SC) plays central roles in ocular physiology. These roles depend on the
molecular phenotypes of SC endothelial cells (SECs). Both the specific phenotype of SECs …

Vascular endothelial cells (ECs) form the inner lining of all blood vessels from the largest
artery and veins, viz., the aorta and venae cavae, respectively, to the capillaries that connect …

In search of redox mechanisms in breast cancer, we uncovered a striking role for glutathione
peroxidase 2 (GPx2) in oncogenic signaling and patient survival. GPx2 loss stimulates …

Angiogenesis is known as one of the hallmarks in cancer which could play a key role in
providing oxygen and nutrients for tumor cells. It has been shown that tumor cannot grow …