The gut microbiome alterations and inflammation-driven pathogenesis of Alzheimer's disease—a critical review
One of the most important scientific discoveries of recent years was the disclosure that the
intestinal microflora takes part in bidirectional communication between the gut and the brain …
intestinal microflora takes part in bidirectional communication between the gut and the brain …
[HTML][HTML] Antidiabetic agents as a novel treatment for Alzheimer's and Parkinson's disease
J Nowell, E Blunt, D Gupta, P Edison - Ageing Research Reviews, 2023 - Elsevier
Therapeutic strategies for neurodegenerative disorders have commonly targeted individual
aspects of the disease pathogenesis to little success. Neurodegenerative diseases …
aspects of the disease pathogenesis to little success. Neurodegenerative diseases …
Microbiota modulation counteracts Alzheimer's disease progression influencing neuronal proteolysis and gut hormones plasma levels
L Bonfili, V Cecarini, S Berardi, S Scarpona… - Scientific reports, 2017 - nature.com
Gut microbiota has a proven role in regulating multiple neuro-chemical pathways through
the highly interconnected gut-brain axis. Oral bacteriotherapy thus has potential in the …
the highly interconnected gut-brain axis. Oral bacteriotherapy thus has potential in the …
SLAB51 probiotic formulation activates SIRT1 pathway promoting antioxidant and neuroprotective effects in an AD mouse model
The gut-brain axis is a bidirectional communication network functionally linking the gut and
the central nervous system (CNS). Based on this, the rational manipulation of intestinal …
the central nervous system (CNS). Based on this, the rational manipulation of intestinal …
The immunopathogenesis of Alzheimer's disease is related to the composition of gut microbiota
F Leblhuber, D Ehrlich, K Steiner, S Geisler, D Fuchs… - Nutrients, 2021 - mdpi.com
The microbiota–gut–brain axis plays an important role in the development of
neurodegenerative diseases. Commensal and pathogenic enteric bacteria can influence …
neurodegenerative diseases. Commensal and pathogenic enteric bacteria can influence …
Relevance of gutmicrobiota in cognition, behaviour and Alzheimer's disease
V de JR De-Paula, AS Forlenza, OV Forlenza - Pharmacological research, 2018 - Elsevier
Approximately 95% of the symbiotic microbes in human body are located in the gut. This
microbioma is involved in important homeostatic processes, not only related to …
microbioma is involved in important homeostatic processes, not only related to …
Microbiota modulation as preventative and therapeutic approach in Alzheimer's disease
The gut microbiota coevolves with its host, and numerous factors like diet, lifestyle, drug
intake and geographical location continuously modify its composition, deeply influencing …
intake and geographical location continuously modify its composition, deeply influencing …
Multiple roles of short-chain fatty acids in Alzheimer disease
H Chen, L Meng, L Shen - Nutrition, 2022 - Elsevier
Alzheimer disease (AD) is the most common form of neurodegenerative disease in older
adults and has a complicated etiology. Recently, the roles of short-chain fatty acids (SCFAs) …
adults and has a complicated etiology. Recently, the roles of short-chain fatty acids (SCFAs) …
Alzheimer‐associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation
JR Clarke, NM Lyra e Silva, CP Figueiredo… - EMBO molecular …, 2015 - embopress.org
Alzheimer's disease (AD) is associated with peripheral metabolic disorders. Clinical/
epidemiological data indicate increased risk of diabetes in AD patients. Here, we show that …
epidemiological data indicate increased risk of diabetes in AD patients. Here, we show that …
Role of metabolism in neurodegenerative disorders
C Procaccini, M Santopaolo, D Faicchia, A Colamatteo… - Metabolism, 2016 - Elsevier
Along with the increase in life expectancy over the last century, the prevalence of age-
related disorders, such as neurodegenerative diseases continues to rise. This is the case of …
related disorders, such as neurodegenerative diseases continues to rise. This is the case of …