Enhancing the potential preclinical and clinical benefits of quercetin through novel drug delivery systems

R Khursheed, SK Singh, S Wadhwa, M Gulati… - Drug discovery today, 2020 - Elsevier
Highlights•Pharmacological activities and molecular targets of quercetin.•Mechanistic
pathways of quercetin for treating different diseases.•Formulation strategies for improving …

Molecular understanding of the protective role of natural products on isoproterenol-induced myocardial infarction: A review

ZW Wong, PV Thanikachalam… - Biomedicine & …, 2017 - Elsevier
Modern medicine has been used to treat myocardial infarction, a subset of cardiovascular
diseases, and have been relatively effective but not without adverse effects. Consequently …

Effects of curcumin nanoparticles in isoproterenol‐induced myocardial infarction

PM Boarescu, I Chirilă, AE Bulboacă… - Oxidative medicine …, 2019 - Wiley Online Library
Curcumin has anti‐inflammatory, antioxidative, anticarcinogenic, and cardiovascular
protective effects. Our study is aimed at evaluating the effects of pretreatment with curcumin …

Effects of quercetin supplementation on inflammatory factors and quality of life in post‐myocardial infarction patients: a double blind, placebo‐controlled, randomized …

F Dehghani, SH Sezavar Seyedi Jandaghi… - Phytotherapy …, 2021 - Wiley Online Library
Myocardial infarction (MI) is one of the leading causes of death in the world. Epidemiological
studies have shown that dietary flavonoids are inversely related to cardiovascular morbidity …

Heart protective effects and mechanism of quercetin preconditioning on anti-myocardial ischemia reperfusion (IR) injuries in rats

H Liu, X Guo, Y Chu, S Lu - Gene, 2014 - Elsevier
In this study, we investigated the effects and mechanism of quercetin preconditioning on anti-
myocardial ischemia reperfusion (IR) injuries in vivo. Meanwhile, their potential anti …

[HTML][HTML] Attenuation of isoprenaline-induced myocardial infarction by Rheum turkestanicum

A Hosseini, A Rajabian, MA Sobhanifar… - Biomedicine & …, 2022 - Elsevier
Background Oxidative stress plays a major role in the pathogenesis of myocardial infarction.
This study evaluated the cardioprotective effects of the hydroalcoholic extract of Rheum …

[HTML][HTML] Chlorogenic acid prevents acute myocardial infarction in rats by reducing inflammatory damage and oxidative stress

D Wang, L Tian, H Lv, Z Pang, D Li, Z Yao… - Biomedicine & …, 2020 - Elsevier
Recent studies have suggested that the prevention of myocardial infarction (MI) through diet
is very important and that the intake of polyphenol-rich foods can improve cardiovascular …

Natural compounds as lactate dehydrogenase inhibitors: Potential therapeutics for lactate dehydrogenase inhibitors-related diseases

JH Han, EJ Lee, W Park, KT Ha… - Frontiers in …, 2023 - frontiersin.org
Lactate dehydrogenase (LDH) is a crucial enzyme involved in energy metabolism and
present in various cells throughout the body. Its diverse physiological functions encompass …

Animal models of myocardial infarction: Mainstay in clinical translation

M Kumar, ER Kasala, LN Bodduluru, V Dahiya… - Regulatory Toxicology …, 2016 - Elsevier
Preclinical models with high prognostic power are a prerequisite for translational research.
The closer the similarity of a model to myocardial infarction (MI), the higher is the prognostic …

Chlorogenic acid ameliorates isoproterenol-induced myocardial injury in rats by stabilizing mitochondrial and lysosomal enzymes

P Akila, L Asaikumar, L Vennila - Biomedicine & Pharmacotherapy, 2017 - Elsevier
This study was deliberated to aspire the effects of chlorogenic acid (CGA) against
myocardial infarction (MI) induced by Isoproterenol (ISO), in a rat model. In the pathology of …