Aseptic loosening and other wear-related complications are some of the most frequent late
reasons for revision of total knee arthroplasty (TKA). Periprosthetic osteolysis (PPOL) pre …

Magnetic particle imaging (MPI) is an emerging biomedical imaging technology that allows
the direct quantitative mapping of the spatial distribution of superparamagnetic iron oxide …

Highly cross-linked ultra-high molecular weight polyethylene (UHMWPE) decreases wear at
the hip by more than 50% compared with conventional UHMWPE. However, melted highly …

Aims The purpose of this study was to compare the long-term results of primary total hip
arthroplasty (THA) in young patients using either a conventional (CPE) or a highly cross …

Wear debris related osteolysis is recognised as being the main cause of failure in joint
replacements based on UHMWPE inserts. However, many solutions and “new” …

Background: The use of highly cross-linked polyethylene is now commonplace in total hip
arthroplasty. Hip simulator studies and short-term in vivo measurements have suggested …

The destruction of bone around joint replacements (periprosthetic osteolysis) is an adverse
biological response associated with the generation of excessive wear particles. Wear debris …

The creep and wear behaviour of highly cross-linked polyethylene and standard
polyethylene liners were examined in a prospective, double-blind randomised, controlled …

In the past, synthetic conventional materials have not served as satisfactory implants. As an
example, the current average lifetime of an orthopedic implant (such as hip, knee, ankle …

Osteolysis ranks as the most significant cause of revision surgery in both total hip
arthroplasty and total knee arthroplasty (TKA). The factors leading to osteolysis in TKA are …