[HTML][HTML] The ACE2/angiotensin-(1–7)/MAS axis of the renin-angiotensin system: focus on angiotensin-(1–7)

RAS Santos, WO Sampaio, AC Alzamora… - Physiological …, 2017 - journals.physiology.org
The renin-angiotensin system (RAS) is a key player in the control of the cardiovascular
system and hydroelectrolyte balance, with an influence on organs and functions throughout …

ACE2, angiotensin‐(1‐7) and M as receptor axis in inflammation and fibrosis

AC Simões e Silva, KD Silveira… - British journal of …, 2013 - Wiley Online Library
Recent advances have improved our understanding of the renin‐angiotensin system (RAS).
These have included the recognition that angiotensin (A ng)‐(1‐7) is a biologically active …

ACE inhibition, ACE2 and angiotensin-(1⿿ 7) axis in kidney and cardiac inflammation and fibrosis

ACS e Silva, MM Teixeira - Pharmacological research, 2016 - Elsevier
Abstract The Renin Angiotensin System (RAS) is a pivotal physiological regulator of heart
and kidney homeostasis, but also plays an important role in the pathophysiology of heart …

Anti-inflammatory effects of angiotensin-(1-7) in ischemic stroke

RW Regenhardt, F Desland, AP Mecca, DJ Pioquinto… - …, 2013 - Elsevier
Previously we demonstrated that central administration of angiotensin-(1-7)[Ang-(1-7)] into
rats elicits significant cerebroprotection against ischemic stroke elicited by endothelin-1 …

[HTML][HTML] The non-classical renin-angiotensin system and renal function

MC Chappell - Comprehensive Physiology, 2012 - ncbi.nlm.nih.gov
The renin-angiotensin-system (RAS) constitutes one of the most important hormonal
systems in the physiological regulation of blood pressure through renal and non-renal …

Neuroprotective mechanisms of the ACE2–Angiotensin-(1-7)–Mas axis in stroke

DM Bennion, E Haltigan, RW Regenhardt… - Current hypertension …, 2015 - Springer
The discovery of beneficial neuroprotective effects of the angiotensin converting enzyme 2–
angiotensin-(1-7)–Mas axis [ACE2–Ang-(1-7)–Mas] in ischemic and hemorrhagic stroke has …

Mas receptor: a potential strategy in the management of ischemic cardiovascular diseases

A Molaei, E Molaei, AW Hayes, G Karimi - Cell Cycle, 2023 - Taylor & Francis
MasR is a critical element in the RAS accessory pathway that protects the heart against
myocardial infarction, ischemia-reperfusion injury, and pathological remodeling by …

Angiotensin-(1–7) in kidney disease: a review of the controversies

D Zimmerman, KD Burns - Clinical science, 2012 - portlandpress.com
Ang-(1–7)[angiotensin-(1–7)] is a biologically active heptapeptide component of the RAS
(renin–angiotensin system), and is generated in the kidney at relatively high levels, via …

[HTML][HTML] Angiotensin-(1-7): a novel peptide to treat hypertension and nephropathy in diabetes?

RS Padda, Y Shi, CS Lo, SL Zhang… - Journal of diabetes & …, 2015 - ncbi.nlm.nih.gov
The renin-angiotensin system (RAS) plays a pivotal role in mammalian homeostasis
physiology. The RAS can be delineated into a classical RAS (the pressor arm) including …

[HTML][HTML] LPS-induced renal inflammation is prevented by (−)‐epicatechin in rats

PD Prince, L Fischerman, JE Toblli, CG Fraga… - Redox biology, 2017 - Elsevier
This work investigated the capacity of (−)-epicatechin to prevent the renal damage induced
by LPS administration in rats. Male Sprague Dawley rats were fed for 4 days a diet without or …