[HTML][HTML] Human microglial models to study HIV infection and neuropathogenesis: a literature overview and comparative analyses
HIV persistence in the CNS despite antiretroviral therapy may cause neurological disorders
and poses a critical challenge for HIV cure. Understanding the pathobiology of HIV-infected …
and poses a critical challenge for HIV cure. Understanding the pathobiology of HIV-infected …
[HTML][HTML] Microglia in a dish—which techniques are on the menu for functional studies?
P Aktories, P Petry, K Kierdorf - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Microglia build the first line of defense in the central nervous system (CNS) and play central
roles during development and homeostasis. Indeed, they serve a plethora of diverse …
roles during development and homeostasis. Indeed, they serve a plethora of diverse …
[HTML][HTML] Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction
AM Sabogal-Guáqueta, A Marmolejo-Garza… - Nature …, 2023 - nature.com
Metabolic reprogramming is a hallmark of the immune cells in response to inflammatory
stimuli. This metabolic process involves a switch from oxidative phosphorylation (OXPHOS) …
stimuli. This metabolic process involves a switch from oxidative phosphorylation (OXPHOS) …
Gypenoside pretreatment alleviates the cerebral ischemia injury via inhibiting the microglia-mediated neuroinflammation
X Xia, J Chen, H Ren, C Zhou, Q Zhang, H Cheng… - Molecular …, 2024 - Springer
Neuroinflammation is closely related to prognosis in ischemic stroke. Microglia are the main
immune cells in the nervous system. Under physiological conditions, microglia participate in …
immune cells in the nervous system. Under physiological conditions, microglia participate in …
[HTML][HTML] Modulation of Microglial Function by ATP-Gated P2X7 Receptors: Studies in Rat, Mice and Human
P2X receptors are a family of seven ATP-gated ion channels that trigger physiological and
pathophysiological responses in a variety of cells. Five of the family members are sensitive …
pathophysiological responses in a variety of cells. Five of the family members are sensitive …
Mesenchymal stromal cells suppress microglial activation and tumor necrosis factor production
L Xu, H Min, A Saha, A Gunaratne, J Schwartzman… - Cytotherapy, 2024 - Elsevier
Background aims White matter diseases are commonly associated with microglial activation
and neuroinflammation. Mesenchymal stromal cells (MSCs) have immunomodulatory …
and neuroinflammation. Mesenchymal stromal cells (MSCs) have immunomodulatory …