[HTML][HTML] Towards actualizing the value potential of Korea Health Insurance Review and Assessment (HIRA) data as a resource for health research: strengths …

JA Kim, S Yoon, LY Kim… - Journal of Korean medical …, 2017 - synapse.koreamed.org
Health Insurance and Review Assessment (HIRA) in South Korea, also called National
Health Insurance (NHI) data, is a repository of claims data collected in the process of …

Industry sponsorship and research outcome

A Lundh, J Lexchin, B Mintzes… - … of systematic reviews, 2017 - cochranelibrary.com
Background Clinical research affecting how doctors practice medicine is increasingly
sponsored by companies that make drugs and medical devices. Previous systematic …

Availability of evidence of benefits on overall survival and quality of life of cancer drugs approved by European Medicines Agency: retrospective cohort study of drug …

C Davis, H Naci, E Gurpinar, E Poplavska, A Pinto… - bmj, 2017 - bmj.com
Objective To determine the availability of data on overall survival and quality of life benefits
of cancer drugs approved in Europe. Design Retrospective cohort study. Setting Publicly …

Evolution of the randomized clinical trial in the era of precision oncology

JC Del Paggio, JS Berry, WM Hopman… - JAMA …, 2021 - jamanetwork.com
Importance The randomized clinical trial (RCT) in oncology has evolved since its
widespread adoption in the 1970s. In recent years, concerns have emerged regarding the …

An analysis of contemporary oncology randomized clinical trials from low/middle-income vs high-income countries

JC Wells, S Sharma, JC Del Paggio… - JAMA …, 2021 - jamanetwork.com
Importance The burden of cancer falls disproportionally on low-middle–income countries
(LMICs). It is not well known how novel therapies are tested in current clinical trials and the …

[HTML][HTML] Randomised controlled trials and population-based observational research: partners in the evolution of medical evidence

CM Booth, IF Tannock - British journal of cancer, 2014 - nature.com
Recent reports have highlighted the distinct roles and occasional tension between
randomised controlled trials (RCTs) and population-based observational research (Concato …

Factors associated with age disparities among cancer clinical trial participants

EB Ludmir, W Mainwaring, TA Lin, AB Miller… - JAMA …, 2019 - jamanetwork.com
Importance Seminal investigation 2 decades ago alerted the oncology community to age
disparities in participation in cooperative group trials; less is known about whether these …

Delivering affordable cancer care in high-income countries

R Sullivan, J Peppercorn, K Sikora, J Zalcberg… - The lancet …, 2011 - thelancet.com
The burden of cancer is growing, and the disease is becoming a major economic
expenditure for all developed countries. In 2008, the worldwide cost of cancer due to …

The strength of association between surrogate end points and survival in oncology: a systematic review of trial-level meta-analyses

V Prasad, C Kim, M Burotto… - JAMA internal medicine, 2015 - jamanetwork.com
Importance The strength of association between surrogate end points and survival in
oncology is important to understand because surrogate end points are frequently used in …

Participation of lower and upper middle–income countries in oncology clinical trials led by high-income countries

F Rubagumya, WM Hopman, B Gyawali… - JAMA Network …, 2022 - jamanetwork.com
Importance Many randomized clinical trials (RCTs) led by high-income countries (HICs) now
enroll patients from lower middle–income countries (LMICs) and upper middle–income …