Insights into Ganoderma fungi meroterpenoids opening a new era of racemic natural products in mushrooms

JJ Zhang, FY Qin, YX Cheng - Medicinal Research Reviews, 2024 - Wiley Online Library
Ganoderma meroterpenoids (GMs) containing 688 structures to date were discovered to
have multiple remarkable biological activities. 65.6% of meroterpenoids featuring …

Palladium(II)‐Catalyzed Nondirected Late‐Stage C(sp2)−H Deuteration of Heteroarenes Enabled Through a Multi‐Substrate Screening Approach

J Dey, S Kaltenberger… - Angewandte Chemie …, 2024 - Wiley Online Library
The importance of deuterium labelling in a variety of applications, ranging from mechanistic
studies to drug‐discovery, has spurred immense interest in the development of new …

The Role of Ligands and Silver (I) Additives in the Ligand-Promoted Divergent α, β-Dehydrogenation of Aliphatic Acids

Z Li, Y Tang, M Lei - ACS Catalysis, 2024 - ACS Publications
Herein, the density functional theory method was employed to investigate the mechanism of
the ligand-promoted divergent α, β-dehydrogenation of aliphatic acids. The calculated …

Palladium-Catalyzed Hydroalkoxycarbonylation and Hydroxycarbonylation of Cyclopent-3-en-1-ols: Divergent Synthesis of Bridged Cyclic Lactones and β, γ …

M Chen, Y Li, ZH Guan - Organic Letters, 2023 - ACS Publications
Herein, we report a palladium-catalyzed hydroalkoxycarbonylation and
hydroxycarbonylation of cyclopent-3-en-1-ols to form bridged bicyclic lactones and β, γ …

Palladium catalyzed C (sp3)–H bond activation of free carboxylic acids: An adventure of ligand evolution

D Li, XB He, L Jin, X Yu, Q Zhang - Tetrahedron Letters, 2024 - Elsevier
One of the core goals of C single bond H activation is to utilize native functional groups
(such as free carboxylic acids) as directing groups (DGs), which would omit the steps for DG …

Ligand‐Enabled Double γ‐C(sp3)−H Functionalization of Aliphatic Acids: One‐Step Synthesis of γ‐Arylated γ‐Lactones

ME Hoque, JQ Yu - Angewandte Chemie, 2023 - Wiley Online Library
Abstract γ‐methylene C (sp3)− H functionalization of linear free carboxylic acids remains a
significant challenge. Here in we report a Pd (II)‐catalyzed tandem γ‐arylation and γ …

Electrochemical Synthesis of Spirolactones from α-Tetralone Derivatives with Methanol as a C1 Source

W Xiao, J Wang, J Ye, H Wang, J Wu, S Ye - Organic Letters, 2024 - ACS Publications
Spirolactones are widely found in pharmaceuticals and bioactive natural products. However,
efficient and environmentally friendly approaches to accessing spirolactones are still highly …

Ru (II)-Catalyzed Divergent C–H Alkynylation Cascade with Bifunctional α-Alcohol Haloalkynes

Q Zhang, Y Li, Y Chen, J Jiang, Y Liu, J Luo… - Organic …, 2024 - ACS Publications
Native functionality directed the C–H activation cascade to enable rapid construction of
molecular complexity, featuring step-economy and synthetic efficiency. Herein, by exploiting …

Nickel-Catalyzed Arylation/Lactonization Cascade Reactions for the Synthesis of Bicyclo [3.2. 1] lactones

A Pounder, E Neufeld, LD Chen, W Tam - Organometallics, 2024 - ACS Publications
An experimental and theoretical investigation of the nickel-catalyzed arylative ring-
opening/lactonization cascade reactions of oxabicyclic alkenes with aryl halides is reported …

[HTML][HTML] Palladium (II)-catalyzed cascade reactions initiated with directed activation of unactivated sp3 C–H bonds

R Ge, F Herington, A Mangawang, D Maiti, H Ge - Tetrahedron Chem, 2023 - Elsevier
Cascade reactions—chemical processes consisting of two or more reactions in one pot—
offer considerable advantages in terms of time, cost, atom efficiency, and reduced waste …