The recent outbreak of the corona virus disease (COVID-19) has had major global impact.
The relationship between severe acute respiratory syndrome coronavirus (SARS-CoV-2) …

Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

The past decade has seen a steady accumulation of evidence supporting a role for the
excitatory amino acid (EAA) neurotransmitter, glutamate, and its receptors in depression and …

Berberine, an alkaloid isolated from Berberis aristata Linn. has been used in the Indian
system of medicines as a stomachic, bitter tonic, antiamoebic and also in the treatment of …

Personalized medicine—the adaptation of therapies based on an individual's genetic and
molecular profile—is one of the most promising aspects of modern medicine. The …

Rationale Systemic inhibition of neuronal nitric oxide synthase (nNOS) induces
antidepressant-like effects in rodents. The mechanisms and brain regions mediating this …

Intense research has been conducted in an effort to identify specific biological markers of
schizophrenia. The gas nitric oxide (NO) is one of the most important signaling molecules …

Nitric oxide (NO) has been implicated to play a role in the pathogenesis of many
neuropsychiatric disorders. NO level was found high in acute manic inpatients. In this study …

Affective disorders including major depressive disorder (MDD), bipolar disorder (BPD), and
general anxiety affect more than 10% of population in the world. Notably, neuronal nitric …

BACKGROUND: There is evidence that inflammation, oxidative and nitrosative stress
(IO&NS) play a role in the pathophysiology of depression. There are also data indicating …