Short chain fatty acids: microbial metabolites for gut-brain axis signalling

KJ O'Riordan, MK Collins, GM Moloney… - Molecular and Cellular …, 2022 - Elsevier
The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to
prominence in recent years. Understanding the relationship between the gut microbiota, the …

Gut microbiota-derived metabolites as central regulators in metabolic disorders

A Agus, K Clément, H Sokol - Gut, 2021 - gut.bmj.com
Metabolic disorders represent a growing worldwide health challenge due to their
dramatically increasing prevalence. The gut microbiota is a crucial actor that can interact …

The gut microbiota and inflammation: an overview

Z Al Bander, MD Nitert, A Mousa… - International journal of …, 2020 - mdpi.com
The gut microbiota encompasses a diverse community of bacteria that carry out various
functions influencing the overall health of the host. These comprise nutrient metabolism …

The effect of probiotics on the production of short-chain fatty acids by human intestinal microbiome

P Markowiak-Kopeć, K Śliżewska - Nutrients, 2020 - mdpi.com
The relationship between diet and the diversity and function of the intestinal microbiome and
its importance for human health is currently the subject of many studies. The type and …

Short-chain fatty acids in diseases

D Zhang, YP Jian, YN Zhang, Y Li, LT Gu… - Cell Communication and …, 2023 - Springer
Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation
of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate …

The protective role of butyrate against obesity and obesity-related diseases

S Coppola, C Avagliano, A Calignano, R Berni Canani - Molecules, 2021 - mdpi.com
Worldwide obesity is a public health concern that has reached pandemic levels. Obesity is
the major predisposing factor to comorbidities, including type 2 diabetes, cardiovascular …

Monounsaturated fatty acids in obesity-related inflammation

G Ravaut, A Légiot, KF Bergeron… - International journal of …, 2020 - mdpi.com
Obesity is an important aspect of the metabolic syndrome and is often associated with
chronic inflammation. In this context, inflammation of organs participating in energy …

Short chain fatty acids in the colon and peripheral tissues: a focus on butyrate, colon cancer, obesity and insulin resistance

SM McNabney, TM Henagan - Nutrients, 2017 - mdpi.com
Increased dietary fiber consumption has been associated with many beneficial effects,
including amelioration of obesity and insulin resistance. These effects may be due to the …

Gut liver brain axis in diseases: the implications for therapeutic interventions

M Yan, S Man, B Sun, L Ma, L Guo, L Huang… - Signal Transduction and …, 2023 - nature.com
Gut-liver-brain axis is a three-way highway of information interaction system among the
gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough …

Human-origin probiotic cocktail increases short-chain fatty acid production via modulation of mice and human gut microbiome

R Nagpal, S Wang, S Ahmadi, J Hayes, J Gagliano… - Scientific reports, 2018 - nature.com
The gut bacteria producing metabolites like short-chain fatty acids (SCFAs; eg, acetate,
propionate and butyrate), are frequently reduced in Patients with diabetes, obesity …