The ocular tissue microenvironment is immune-privileged and uses multiple
immunosuppressive mechanisms to prevent the induction of inflammation. The retinal …

Characterised by intraocular inflammation, non‐infectious uveitis includes a large group of
autoimmune and autoinflammatory diseases that either involve the eye alone or have both …

Background We previously reported higher plasma levels of complement fragments C3a
and C5a in neovascular Age-related Macular Degeneration (nAMD) patients with macular …

Blood-retinal barrier (BRB) disruption is a common accompaniment of intermediate,
posterior and panuveitis causing leakage into the retina and macular oedema resulting in …

The retina is a light-sensing ocular tissue that sends information to the brain to enable
vision. The blood–retinal barrier (BRB) contributes to maintaining homeostasis in the retinal …

Inflammation plays a crucial role in the etiology and pathogenesis of AMD (Age-related
Macular Degeneration). Humanin G (HNG) is a Mitochondrial Derived Peptide (MDP) that is …

To investigate the effect of scutellarin (SCU) in diabetic retinopathy (DR) and explore the
associated molecular network mechanism. The animal model of DR was established from …

Inflammation is key to the pathogenesis of diabetic retinopathy (DR). This prospective study
investigated alterations in inflammatory cytokines in peripheral blood mononuclear cells …

Diabetic retinopathy (DR) is a prevalent complication of diabetes, significantly impacting
patients' quality of life due to vision loss. No pharmacological therapies are currently …

There are~ 463 million diabetics worldwide, and more than half have diabetic retinopathy.
Yet, treatments are still lacking for non-proliferative diabetic retinopathy. We and others …