We describe and discuss a simple dry-compression technique for preparing a flat cuboid
chromatography device containing a shallow packed-bed of crystalline hydroxyapatite …

Viruses are an emerging class of biotherapeutics used to treat a variety of diseases. Ion-
exchange membrane chromatography is commonly used for virus purification, with the …

Cation exchange (CEX) chromatography is widely used for large-scale separation of
monoclonal antibody (mAb) aggregates. The aggregates bind more strongly to CEX media …

The use of conventional membrane adsorbers such as radial flow devices is largely
restricted to flow-through applications, such as virus and endotoxin removal, as they fail to …

Disc membrane chromatography modules are widely used for laboratory-scale protein
separations. These have high radial to axial aspect ratios, with the inlet and the outlet being …

Radial-flow membrane chromatography is widely used for biopharmaceutical purification,
particularly for separations carried out in the flow-through mode. In this article, we propose …

A method of forming a frame around a membrane stack for a laterally-fed membrane
chromatography device is provided. The method includes placing a membrane stack having …

A chromatography device for removing a solute from a fluid is provided. The device has a
first plate having an inlet and a first channel. The first channel directs the fluid from the inlet …

A chromatography device having a housing formed from an upper housing ultrasonically
welded to a lower housing. A compression extension and a boss located inside of the …