A guide to the composition and functions of the extracellular matrix
Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …
provides structural support for the cells and tissues. Accumulated knowledge clearly …
Elastic fibers: Formation, function, and fate during aging and disease
CEH Schmelzer, L Duca - The FEBS Journal, 2022 - Wiley Online Library
Elastic fibers are extracellular components of higher vertebrates and confer elasticity and
resilience to numerous tissues and organs such as large blood vessels, lungs, and skin …
resilience to numerous tissues and organs such as large blood vessels, lungs, and skin …
Sialidase inhibitors with different mechanisms
JM Keil, GR Rafn, IM Turan, MA Aljohani… - Journal of medicinal …, 2022 - ACS Publications
Sialidases, or neuraminidases, are enzymes that catalyze the hydrolysis of sialic acid (Sia)-
containing molecules, mostly removal of the terminal Sia (desialylation). By desialylation …
containing molecules, mostly removal of the terminal Sia (desialylation). By desialylation …
Sialic acid metabolism as a potential therapeutic target of atherosclerosis
C Zhang, J Chen, Y Liu, D Xu - Lipids in health and disease, 2019 - Springer
Sialic acid (Sia), the acylated derivative of the nine-carbon sugar neuraminic acid, is a
terminal component of the oligosaccharide chains of many glycoproteins and glycolipids. In …
terminal component of the oligosaccharide chains of many glycoproteins and glycolipids. In …
The role of elastin-derived peptides in human physiology and diseases
Once considered as inert, the extracellular matrix recently revealed to be biologically active.
Elastin is one of the most important components of the extracellular matrix. Many vital organs …
Elastin is one of the most important components of the extracellular matrix. Many vital organs …
Impact of protein glycosylation on lipoprotein metabolism and atherosclerosis
Protein glycosylation is a post-translational modification consisting in the enzymatic
attachment of carbohydrate chains to specific residues of the protein sequence. Several …
attachment of carbohydrate chains to specific residues of the protein sequence. Several …
The elastin receptor complex: An emerging therapeutic target against age-related vascular diseases
D Tembely, A Henry, L Vanalderwiert… - Frontiers in …, 2022 - frontiersin.org
The incidence of cardiovascular diseases is increasing worldwide with the growing aging of
the population. Biological aging has major influence on the vascular tree and is associated …
the population. Biological aging has major influence on the vascular tree and is associated …
Extracellular matrix: paving the way to the newest trends in atherosclerosis
C Gialeli, A Shami, I Gonçalves - Current opinion in lipidology, 2021 - journals.lww.com
Extracellular matrix: paving the way to the newest trends in... : Current Opinion in Lipidology
Extracellular matrix: paving the way to the newest trends in atherosclerosis : Current Opinion …
Extracellular matrix: paving the way to the newest trends in atherosclerosis : Current Opinion …
Polysialic acid in the immune system
TM Villanueva-Cabello… - Frontiers in …, 2022 - frontiersin.org
Polysialic acid (polySia) is a highly regulated polymer of sialic acid (Sia) with such potent
biophysical characteristics that when expressed drastically influences the interaction …
biophysical characteristics that when expressed drastically influences the interaction …
Prognostic value of elevated levels of plasma N-Acetylneuraminic acid in patients with heart failure
C Li, M Zhao, L Xiao, H Wei, Z Wen, D Hu… - Circulation: Heart …, 2021 - Am Heart Assoc
Background: Cardiac sialylation is involved in a variety of physiological processes in the
heart. Altered sialylation has been implicated in heart failure (HF) mice. However, its role in …
heart. Altered sialylation has been implicated in heart failure (HF) mice. However, its role in …