The role of reactive oxygen species and metabolism on cancer cells and their microenvironment
A Costa, A Scholer-Dahirel… - Seminars in cancer biology, 2014 - Elsevier
Compelling evidence show that reactive oxygen species (ROS) levels are finely regulated in
the cell and can act as “second messengers” in response to diverse stimuli. In tumor …
the cell and can act as “second messengers” in response to diverse stimuli. In tumor …
The antioxidative function of alpha‐ketoglutarate and its applications
S Liu, L He, K Yao - BioMed research international, 2018 - Wiley Online Library
Alpha‐ketoglutarate (AKG) is a crucial intermediate of the Krebs cycle and plays a critical
role in multiple metabolic processes in animals and humans. Of note, AKG contributes to the …
role in multiple metabolic processes in animals and humans. Of note, AKG contributes to the …
Antioxidant Effects of Different Extracts from Melissa officinalis, Matricaria recutita and Cymbopogon citratus
RP Pereira, R Fachinetto, A de Souza Prestes… - Neurochemical …, 2009 - Springer
Considering the important role of oxidative stress in the pathogenesis of several
neurological diseases, and the growing evidence of the presence of compounds with …
neurological diseases, and the growing evidence of the presence of compounds with …
Mutant p53-associated molecular mechanisms of ROS regulation in cancer cells
M Cordani, G Butera, R Pacchiana, F Masetto… - Biomolecules, 2020 - mdpi.com
The TP53 tumor suppressor gene is the most frequently altered gene in tumors and an
increasing number of studies highlight that mutant p53 proteins can acquire oncogenic …
increasing number of studies highlight that mutant p53 proteins can acquire oncogenic …
New organochalcogen multitarget drug: Synthesis and antioxidant and antitumoral activities of chalcogenozidovudine derivatives
In this article we present the synthesis, characterization, and in vitro biological and
biochemical activities of new chalcogenozidovudine derivatives as antioxidant (inhibition of …
biochemical activities of new chalcogenozidovudine derivatives as antioxidant (inhibition of …
Diphenyl Diselenide Protects Against Mortality, Locomotor Deficits and Oxidative Stress in Drosophila melanogaster Model of Manganese-Induced Neurotoxicity
Several experimental and epidemiological reports have associated manganese exposure
with induction of oxidative stress and locomotor dysfunctions. Diphenyl diselenide (DPDS) is …
with induction of oxidative stress and locomotor dysfunctions. Diphenyl diselenide (DPDS) is …
Glutamate attenuates lipopolysaccharide-induced oxidative damage and mRNA expression changes of tight junction and defensin proteins, inflammatory and …
J Jiang, L Yin, JY Li, Q Li, D Shi, L Feng, Y Liu… - Fish & Shellfish …, 2017 - Elsevier
The present study explored the possible preventive effects of dietary glutamate (Glu) on LPS-
induced oxidative damage, mRNA expression changes of tight junction (TJ) and defensin …
induced oxidative damage, mRNA expression changes of tight junction (TJ) and defensin …
Chemical composition, antioxidant and anticholinesterase activity of Melissa officinalis
RP Pereira, AA Boligon, AS Appel, R Fachinetto… - Industrial Crops and …, 2014 - Elsevier
Oxidative stress is associated with various diseases, in particular those related with the
central nervous system, such as Alzheimer's disease. Based on the various benefits of …
central nervous system, such as Alzheimer's disease. Based on the various benefits of …
Diphenyl diselenide, a simple organoselenium compound, decreases methylmercury-induced cerebral, hepatic and renal oxidative stress and mercury deposition in …
AS de Freitas, VR Funck, M dos Santos Rotta… - Brain Research …, 2009 - Elsevier
Oxidative stress has been pointed out as an important molecular mechanism in
methylmercury (MeHg) intoxication. At low doses, diphenyl diselenide ((PhSe) 2), a …
methylmercury (MeHg) intoxication. At low doses, diphenyl diselenide ((PhSe) 2), a …
Effect of reactive oxygen species overproduction on osteogenesis of porous titanium implant in the present of diabetes mellitus
YF Feng, L Wang, Y Zhang, X Li, ZS Ma, JW Zou, W Lei… - Biomaterials, 2013 - Elsevier
Clinical evidence indicates diabetes as a majorrisk factor for titaniumimplant treatment with
high failure rates and poor osteointegration, but the underlying mechanism involved remains …
high failure rates and poor osteointegration, but the underlying mechanism involved remains …