Colorectal cancers (CRCs) with deficient mismatch repair (dMMR) or microsatellite instability-
high (MSI-H) often have sustained responses to immune checkpoint inhibitors (ICIs) …

Repetitive DNA motifs are abundant in the genomes of various species and have the
capacity to adopt non-canonical (ie, non-B) DNA structures. Several non-B DNA structures …

Tandem repeat (TR) expansions have been implicated in dozens of genetic diseases,
including Huntington's Disease, Fragile X Syndrome, and hereditary ataxias. Furthermore …

Nonrecombining Y-chromosomal microsatellites (Y-STRs) are widely used to infer
population histories, discover genealogical relationships, and identify males for criminal …

G‐quadruplexes are four‐stranded nucleic acid structures whose biological functions
remain poorly understood. In the yeast S. cerevisia e, we report that G‐quadruplexes form …

Short tandem repeats (STRs) are units of 1–6 bp that repeat in a tandem fashion in DNA.
Along with single nucleotide polymorphisms and large structural variations, they are among …

Tandem repeats are genomic elements that are prone to changes in repeat number and are
thus often polymorphic. These sequences are found at a high density at the start of human …

Gross chromosomal rearrangements (including translocations, deletions, insertions and
duplications) are a hallmark of cancer genomes and often create oncogenic fusion genes …

We now present the first example in which triplet repeat DNAs adopt the i-motif structure at
neutral pH by molecular crowding. Crowding stabilized the i-motif and the pKa of N3 of …

This review presents detailed information about the structure of triplet repeat RNA and
addresses the simple sequence repeats of normal and expanded lengths in the context of …