DNA origami

S Dey, C Fan, KV Gothelf, J Li, C Lin, L Liu… - Nature Reviews …, 2021 - nature.com
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …

Functionalizing framework nucleic‐acid‐based nanostructures for biomedical application

T Zhang, T Tian, Y Lin - Advanced Materials, 2022 - Wiley Online Library
Strategies for functionalizing diverse tetrahedral framework nucleic acids (tFNAs) have been
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …

Functional DNA regulated CRISPR-Cas12a sensors for point-of-care diagnostics of non-nucleic-acid targets

Y Xiong, J Zhang, Z Yang, Q Mou, Y Ma… - Journal of the …, 2019 - ACS Publications
Beyond its extraordinary genome editing ability, the CRISPR-Cas systems have opened a
new era of biosensing applications due to its high base resolution and isothermal signal …

Rationally engineered nucleic acid architectures for biosensing applications

M Xiao, W Lai, T Man, B Chang, L Li… - Chemical …, 2019 - ACS Publications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

DNA nanotechnology-empowered nanoscopic imaging of biomolecules

F Li, J Li, B Dong, F Wang, C Fan, X Zuo - Chemical Society Reviews, 2021 - pubs.rsc.org
Advances in bioimaging technologies have led to unprecedented findings of novel
biological processes at the nanoscale. However, there remains an ever-lasting demand for …

Construction of fast-walking tetrahedral DNA walker with four arms for sensitive detection and intracellular imaging of apurinic/apyrimidinic endonuclease 1

XM Zhou, Y Zhuo, TT Tu, R Yuan, YQ Chai - Analytical chemistry, 2022 - ACS Publications
Herein, a novel tetrahedral DNA walker with four arms was engineered to travel efficiently on
the 3D-tracks via catalyzed hairpin assembly autonomously, realizing the sensitive detection …

Single-stranded DNA-encoded gold nanoparticle clusters as programmable enzyme equivalents

X Chen, Y Wang, X Dai, L Ding, J Chen… - Journal of the …, 2022 - ACS Publications
Nanozymes have emerged as a class of novel catalytic nanomaterials that show great
potential to substitute natural enzymes in various applications. Nevertheless, spatial …

Conjugated polymers for biomedical applications

H Lin, H Bai, Z Yang, Q Shen, M Li, Y Huang… - Chemical …, 2022 - pubs.rsc.org
Conjugated polymers (CPs) are a series of organic semiconductor materials with large π-
conjugated backbones and delocalized electronic structures. Due to their specific …

Engineering DNA on the surface of upconversion nanoparticles for bioanalysis and therapeutics

D Zhang, R Peng, W Liu, MJ Donovan, L Wang… - ACS …, 2021 - ACS Publications
Surface modification of inorganic nanomaterials with biomolecules has enabled the
development of composites integrated with extensive properties. Lanthanide ion-doped …

Target-responsive smart nanomaterials via a Au–S binding encapsulation strategy for electrochemical/colorimetric dual-mode paper-based analytical devices

X Zhang, H Zhi, F Wang, M Zhu, H Meng… - Analytical …, 2022 - ACS Publications
Target-responsive nanomaterials attract growing interest in the application of drug delivery,
bioimaging, and sensing due to the responsive releasing of guest molecules by the smart …