DNA origami
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …
Functionalizing framework nucleic‐acid‐based nanostructures for biomedical application
T Zhang, T Tian, Y Lin - Advanced Materials, 2022 - Wiley Online Library
Strategies for functionalizing diverse tetrahedral framework nucleic acids (tFNAs) have been
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …
Functional DNA regulated CRISPR-Cas12a sensors for point-of-care diagnostics of non-nucleic-acid targets
Beyond its extraordinary genome editing ability, the CRISPR-Cas systems have opened a
new era of biosensing applications due to its high base resolution and isothermal signal …
new era of biosensing applications due to its high base resolution and isothermal signal …
Rationally engineered nucleic acid architectures for biosensing applications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …
DNA nanotechnology-empowered nanoscopic imaging of biomolecules
Advances in bioimaging technologies have led to unprecedented findings of novel
biological processes at the nanoscale. However, there remains an ever-lasting demand for …
biological processes at the nanoscale. However, there remains an ever-lasting demand for …
Construction of fast-walking tetrahedral DNA walker with four arms for sensitive detection and intracellular imaging of apurinic/apyrimidinic endonuclease 1
XM Zhou, Y Zhuo, TT Tu, R Yuan, YQ Chai - Analytical chemistry, 2022 - ACS Publications
Herein, a novel tetrahedral DNA walker with four arms was engineered to travel efficiently on
the 3D-tracks via catalyzed hairpin assembly autonomously, realizing the sensitive detection …
the 3D-tracks via catalyzed hairpin assembly autonomously, realizing the sensitive detection …
Single-stranded DNA-encoded gold nanoparticle clusters as programmable enzyme equivalents
X Chen, Y Wang, X Dai, L Ding, J Chen… - Journal of the …, 2022 - ACS Publications
Nanozymes have emerged as a class of novel catalytic nanomaterials that show great
potential to substitute natural enzymes in various applications. Nevertheless, spatial …
potential to substitute natural enzymes in various applications. Nevertheless, spatial …
Conjugated polymers for biomedical applications
Conjugated polymers (CPs) are a series of organic semiconductor materials with large π-
conjugated backbones and delocalized electronic structures. Due to their specific …
conjugated backbones and delocalized electronic structures. Due to their specific …
Engineering DNA on the surface of upconversion nanoparticles for bioanalysis and therapeutics
Surface modification of inorganic nanomaterials with biomolecules has enabled the
development of composites integrated with extensive properties. Lanthanide ion-doped …
development of composites integrated with extensive properties. Lanthanide ion-doped …
Target-responsive smart nanomaterials via a Au–S binding encapsulation strategy for electrochemical/colorimetric dual-mode paper-based analytical devices
X Zhang, H Zhi, F Wang, M Zhu, H Meng… - Analytical …, 2022 - ACS Publications
Target-responsive nanomaterials attract growing interest in the application of drug delivery,
bioimaging, and sensing due to the responsive releasing of guest molecules by the smart …
bioimaging, and sensing due to the responsive releasing of guest molecules by the smart …