Simple Summary Maintenance of telomeres is a fundamental step in human carcinogenesis
and is primarily regulated by telomerase and the human telomerase reverse transcriptase …

One of the hallmarks of cancer cells is their indefinite replicative potential, made possible by
the activation of a telomere maintenance mechanism (TMM). The majority of cancers …

High-grade astrocytoma of WHO grade 4 termed glioblastoma multiforme (GBM) is a
common human brain tumor with poor patient outcome. Astrocytoma demonstrates two …

Abstract Background Histone deacetylases (HDACs) are the proteins responsible for
removing the acetyl group from lysine residues of core histones in chromosomes, a crucial …

In recent years, most related studies have found that chronic hepatitis B virus infection is the
main cause of hepatocellular carcinoma (HCC), but the specific pathogenesis is still unclear …

Simple Summary The alternative lengthening of telomeres is a telomere maintenance
mechanism used by some cancer types to elongate their telomeres without the aid of …

组蛋白去乙酰化酶9 (histone deacetylase 9, HDAC9) 属于组蛋白去乙酰化酶(histone
deacetylases, HDACs) Ⅱa 亚型, 在体内通过催化组蛋白3 (H3), 组蛋白4 (H4) …

组蛋白去乙酰化酶9 在骨髓间充质干细胞衰老过程中的表达 Page 1 4762|中国组织工程研究|第
26卷|第30期|2022年10月 中国组织工程研究 Chinese Journal of Tissue Engineering Research …

Neuroendocrine neoplasms (NENs) represent a diverse collection of malignancies with
heterogenous cell and tissue of origin, clinical behavior, and genetic underpinnings. This …

Cancer cells activate a telomere maintenance mechanism like telomerase in order to
proliferate indefinitely. Telomerase can be reactivated by gain-of-function Telomerase …