Highlights•Genetic improvement of crops is a key strategy to adapt to climate change.•Plants
will be required for both changing field environments and new protected environments.• …

Through four decades' development, DNA sequencing has inched into the era of single-
molecule sequencing (SMS), or the third-generation sequencing (TGS), as represented by …

Long-read sequencing data, particularly those derived from the Oxford Nanopore
sequencing platform, tend to exhibit high error rates. Here, we present NextDenovo, an …

Long nanopore reads are advantageous in de novo genome assembly. However, nanopore
reads usually have broad error distribution and high-error-rate subsequences. Existing error …

Abstract N 6-Methyladenine (6mA) DNA methylation has recently been implicated as a
potential new epigenetic marker in eukaryotes, including the dicot model Arabidopsis …

Eukaryotic genome sequencing and de novo assembly, once the exclusive domain of well-
funded international consortia, have become increasingly affordable, thus fitting the budgets …

Metagenomic sequencing has allowed for the recovery of previously unexplored microbial
genomes. Whereas short-read sequencing platforms often result in highly fragmented …

Background & Aims Lack of viral reference genomes poses a challenge to virome study. We
investigated human gut virome and its clinical implication by ultra-deep metagenomic …

Understanding the roles of genetic divergence and phenotypic plasticity in adaptation is
central to evolutionary biology and important for assessing adaptive potential of species …

The improvement and decreasing costs of third‐generation sequencing technologies has
widened the scope of biological questions researchers can address with de novo genome …