Aminoacyl-tRNAs: setting the limits of the genetic code
Aminoacyl-tRNAs (aa-tRNAs) are simple molecules with a single purpose—to serve as
substrates for translation. They consist of mature tRNAs to which an amino acid has been …
substrates for translation. They consist of mature tRNAs to which an amino acid has been …
Evolution and variation in amide aminoacyl‐tRNA synthesis
The amide proteogenic amino acids, asparagine and glutamine, are two of the twenty amino
acids used in translation by all known life. The aminoacyl‐tRNA synthetases for asparagine …
acids used in translation by all known life. The aminoacyl‐tRNA synthetases for asparagine …
Acidithiobacillus ferrooxidans metabolism: from genome sequence to industrial applications
J Valdés, I Pedroso, R Quatrini, RJ Dodson, H Tettelin… - BMC genomics, 2008 - Springer
Background Acidithiobacillus ferrooxidans is a major participant in consortia of
microorganisms used for the industrial recovery of copper (bioleaching or biomining). It is a …
microorganisms used for the industrial recovery of copper (bioleaching or biomining). It is a …
[HTML][HTML] Optimization of the heme biosynthesis pathway for the production of 5-aminolevulinic acid in Escherichia coli
J Zhang, Z Kang, J Chen, G Du - Scientific Reports, 2015 - nature.com
Aminolevulinic acid (ALA), the committed intermediate of the heme biosynthesis pathway,
shows significant promise for cancer treatment. Here, we identified that in addition to hemA …
shows significant promise for cancer treatment. Here, we identified that in addition to hemA …
Quality control despite mistranslation caused by an ambiguous genetic code
B Ruan, S Palioura, J Sabina… - Proceedings of the …, 2008 - National Acad Sciences
A high level of accuracy during protein synthesis is considered essential for life. Aminoacyl-
tRNA synthetases (aaRSs) translate the genetic code by ensuring the correct pairing of …
tRNA synthetases (aaRSs) translate the genetic code by ensuring the correct pairing of …
Whole-transcriptome RNA sequencing highlights the molecular mechanisms associated with the maintenance of postharvest quality in broccoli by red LED irradiation
Z Yan, J Shi, S Yuan, S Zheng, L Gao, C Wu… - Postharvest Biology and …, 2022 - Elsevier
Irradiation of green vegetables with different wavelengths of light represents a safe and
effective technology that can be used to maintain postharvest quality. In this regard, our …
effective technology that can be used to maintain postharvest quality. In this regard, our …
Regulation of a glutamyl-tRNA synthetase by the heme status
Glutamyl-tRNA (Glu-tRNA), formed by Glu-tRNA synthetase (GluRS), is a substrate for
protein biosynthesis and tetrapyrrole formation by the C5 pathway. In this route Glu-tRNA is …
protein biosynthesis and tetrapyrrole formation by the C5 pathway. In this route Glu-tRNA is …
The Nondiscriminating Aspartyl-tRNA Synthetase from Helicobacter pylori: Anticodon-Binding Domain Mutations That Impact tRNA Specificity and Heterologous …
P Chuawong, TL Hendrickson - Biochemistry, 2006 - ACS Publications
Divergent tRNA substrate recognition patterns distinguish the two distinct forms of aspartyl-
tRNA synthetase (AspRS) that exist in different bacteria. In some cases, a canonical …
tRNA synthetase (AspRS) that exist in different bacteria. In some cases, a canonical …
[HTML][HTML] A Multi-Omic and physiological Investigation of the impact of 2-ethylhexylglycidylether (EHGE) on the postharvest senescence and yellowing of broccoli
H Guo, T Tian, J Lv, B Yan, S Yuan, X Xu, X Xu, X Yue… - LWT, 2024 - Elsevier
The objective of study was to investigate the underlying mechanisms responsible for the
ability of 2-Ethylhexylglycidylether (EHGE) fumigation to inhibit the yellowing and …
ability of 2-Ethylhexylglycidylether (EHGE) fumigation to inhibit the yellowing and …
Indirect tRNA aminoacylation during accurate translation and phenotypic mistranslation
UM Rathnayake, WN Wood, TL Hendrickson - Current Opinion in Chemical …, 2017 - Elsevier
Highlights•Many bacteria are missing asparaginyl-tRNA and/or glutaminyl-tRNA
synthetase.•Asn-tRNA Asn and Gln-tRNA Gln are produced in a two-step, indirect …
synthetase.•Asn-tRNA Asn and Gln-tRNA Gln are produced in a two-step, indirect …