Aminoacyl-tRNAs: setting the limits of the genetic code

M Ibba, D Söll - Genes & development, 2004 - genesdev.cshlp.org
Aminoacyl-tRNAs (aa-tRNAs) are simple molecules with a single purpose—to serve as
substrates for translation. They consist of mature tRNAs to which an amino acid has been …

Evolution and variation in amide aminoacyl‐tRNA synthesis

AM Lewis, T Fallon, GA Dittemore, K Sheppard - IUBMB life, 2024 - Wiley Online Library
The amide proteogenic amino acids, asparagine and glutamine, are two of the twenty amino
acids used in translation by all known life. The aminoacyl‐tRNA synthetases for asparagine …

Acidithiobacillus ferrooxidans metabolism: from genome sequence to industrial applications

J Valdés, I Pedroso, R Quatrini, RJ Dodson, H Tettelin… - BMC genomics, 2008 - Springer
Background Acidithiobacillus ferrooxidans is a major participant in consortia of
microorganisms used for the industrial recovery of copper (bioleaching or biomining). It is a …

[HTML][HTML] Optimization of the heme biosynthesis pathway for the production of 5-aminolevulinic acid in Escherichia coli

J Zhang, Z Kang, J Chen, G Du - Scientific Reports, 2015 - nature.com
Aminolevulinic acid (ALA), the committed intermediate of the heme biosynthesis pathway,
shows significant promise for cancer treatment. Here, we identified that in addition to hemA …

Quality control despite mistranslation caused by an ambiguous genetic code

B Ruan, S Palioura, J Sabina… - Proceedings of the …, 2008 - National Acad Sciences
A high level of accuracy during protein synthesis is considered essential for life. Aminoacyl-
tRNA synthetases (aaRSs) translate the genetic code by ensuring the correct pairing of …

Whole-transcriptome RNA sequencing highlights the molecular mechanisms associated with the maintenance of postharvest quality in broccoli by red LED irradiation

Z Yan, J Shi, S Yuan, S Zheng, L Gao, C Wu… - Postharvest Biology and …, 2022 - Elsevier
Irradiation of green vegetables with different wavelengths of light represents a safe and
effective technology that can be used to maintain postharvest quality. In this regard, our …

Regulation of a glutamyl-tRNA synthetase by the heme status

G Levicán, A Katz, M De Armas… - Proceedings of the …, 2007 - National Acad Sciences
Glutamyl-tRNA (Glu-tRNA), formed by Glu-tRNA synthetase (GluRS), is a substrate for
protein biosynthesis and tetrapyrrole formation by the C5 pathway. In this route Glu-tRNA is …

The Nondiscriminating Aspartyl-tRNA Synthetase from Helicobacter pylori:  Anticodon-Binding Domain Mutations That Impact tRNA Specificity and Heterologous …

P Chuawong, TL Hendrickson - Biochemistry, 2006 - ACS Publications
Divergent tRNA substrate recognition patterns distinguish the two distinct forms of aspartyl-
tRNA synthetase (AspRS) that exist in different bacteria. In some cases, a canonical …

[HTML][HTML] A Multi-Omic and physiological Investigation of the impact of 2-ethylhexylglycidylether (EHGE) on the postharvest senescence and yellowing of broccoli

H Guo, T Tian, J Lv, B Yan, S Yuan, X Xu, X Xu, X Yue… - LWT, 2024 - Elsevier
The objective of study was to investigate the underlying mechanisms responsible for the
ability of 2-Ethylhexylglycidylether (EHGE) fumigation to inhibit the yellowing and …

Indirect tRNA aminoacylation during accurate translation and phenotypic mistranslation

UM Rathnayake, WN Wood, TL Hendrickson - Current Opinion in Chemical …, 2017 - Elsevier
Highlights•Many bacteria are missing asparaginyl-tRNA and/or glutaminyl-tRNA
synthetase.•Asn-tRNA Asn and Gln-tRNA Gln are produced in a two-step, indirect …