Paracetamol use during pregnancy—a call for precautionary action

AZ Bauer, SH Swan, D Kriebel, Z Liew… - Nature Reviews …, 2021 - nature.com
Abstract Paracetamol (N-acetyl-p-aminophenol (APAP), otherwise known as
acetaminophen) is the active ingredient in more than 600 medications used to relieve mild to …

Anogenital distance as a toxicological or clinical marker for fetal androgen action and risk for reproductive disorders

CL Schwartz, S Christiansen, AM Vinggaard… - Archives of …, 2019 - Springer
Male reproductive development is intricately dependent on fetal androgen action.
Consequently, disrupted androgen action during fetal life can interfere with the development …

Prenatal fever and autism risk

M Hornig, MA Bresnahan, X Che, AF Schultz… - Molecular …, 2018 - nature.com
Some studies suggest that prenatal infection increases risk of autism spectrum disorders
(ASDs). This study was undertaken in a prospective cohort in Norway to examine whether …

Genome-wide meta-analysis of cognitive empathy: heritability, and correlates with sex, neuropsychiatric conditions and cognition

V Warrier, KL Grasby, F Uzefovsky, R Toro… - Molecular …, 2018 - nature.com
We conducted a genome-wide meta-analysis of cognitive empathy using the 'Reading the
Mind in the Eyes' Test (Eyes Test) in 88,056 research volunteers of European Ancestry …

Analgesic use—prevalence, biomonitoring and endocrine and reproductive effects

DM Kristensen, S Mazaud-Guittot… - Nature Reviews …, 2016 - nature.com
Paracetamol and NSAIDs, in particular acetylsalicylic acid (aspirin) and ibuprofen, are
among the most used and environmentally released pharmaceutical drugs. The differences …

Prenatal paracetamol exposure and child neurodevelopment: A review

AZ Bauer, D Kriebel, MR Herbert, CG Bornehag… - Hormones and …, 2018 - Elsevier
Background The non-prescription medication paracetamol (acetaminophen, APAP) is
currently recommended as a safe pain and fever treatment during pregnancy. However …

Over-the-counter analgesics during pregnancy: a comprehensive review of global prevalence and offspring safety

A Zafeiri, RT Mitchell, DC Hay… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Analgesia during pregnancy is often necessary. Due to their widespread
availability, many mothers opt to use over-the-counter (OTC) analgesics. Those analgesic …

Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

DM Kristensen… - Proceedings of the …, 2018 - National Acad Sciences
Concern has been raised over increased male reproductive disorders in the Western world,
and the disruption of male endocrinology has been suggested to play a central role. Several …

Effect of environmental and pharmaceutical exposures on fetal testis development and function: a systematic review of human experimental data

KR Kilcoyne, RT Mitchell - Human Reproduction Update, 2019 - academic.oup.com
BACKGROUND Overall, the incidence of male reproductive disorders has increased in
recent decades. Testicular development during fetal life is crucial for subsequent male …

[HTML][HTML] Sex-specific neurobehavioral and prefrontal cortex gene expression alterations following developmental acetaminophen exposure in mice

BH Baker, EE Rafikian, PB Hamblin, MD Strait… - Neurobiology of …, 2023 - Elsevier
Abstract Acetaminophen (N-acetyl-p-aminophenol (APAP), also known as paracetamol) is
one of the most common medications used by the general population, including pregnant …