The longer-term impacts of Western diet on human cognition and the brain

H Francis, R Stevenson - Appetite, 2013 - Elsevier
Animal work over the last three decades has generated a convincing body of evidence that a
Western diet–one high in saturated fat and refined carbohydrates (HFS diet)–can damage …

High-dimensional investigation of the cerebrospinal fluid to explore and monitor CNS immune responses

M Heming, AL Börsch, H Wiendl, G Meyer zu Hörste - Genome Medicine, 2022 - Springer
The cerebrospinal fluid (CSF) features a unique immune cell composition and is in constant
contact with the brain borders, thus permitting insights into the brain to diagnose and monitor …

Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors

J Theruvath, E Sotillo, CW Mount, CM Graef… - Nature medicine, 2020 - nature.com
Atypical teratoid/rhabdoid tumors (ATRTs) typically arise in the central nervous system
(CNS) of children under 3 years of age. Despite intensive multimodal therapy (surgery …

Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease

M Garcia-Alloza, EM Robbins, SX Zhang-Nunes… - Neurobiology of …, 2006 - Elsevier
Transgenic mice carrying disease-linked forms of genes associated with Alzheimer disease
often demonstrate deposition of the β-amyloid as senile plaques and cerebral amyloid …

A technique for serial collection of cerebrospinal fluid from the cisterna magna in mouse

L Liu, K Duff - Journal of visualized experiments: JoVE, 2008 - pmc.ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a progressive neurodegenerative disease that is pathologically
characterized by extracellular deposition of β-amyloid peptide (Aβ) and intraneuronal …

Changes in amyloid-β and Tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein

LF Maia, SA Kaeser, J Reichwald, M Hruscha… - Science translational …, 2013 - science.org
Altered concentrations of amyloid-β (Aβ) peptide and Tau protein in the cerebrospinal fluid
(CSF) are thought to be predictive markers for Alzheimer's disease (AD). Transgenic mice …

Diet intervention and cerebrospinal fluid biomarkers in amnestic mild cognitive impairment

JL Bayer-Carter, PS Green, TJ Montine… - Archives of …, 2011 - jamanetwork.com
Objective To compare the effects of a 4-week high–saturated fat/high–glycemic index (HIGH)
diet with a low–saturated fat/low–glycemic index (LOW) diet on insulin and lipid metabolism …

An improved method for collection of cerebrospinal fluid from anesthetized mice

NKH Lim, V Moestrup, X Zhang… - Journal of …, 2018 - pmc.ncbi.nlm.nih.gov
The cerebrospinal fluid (CSF) is a valuable body fluid for analysis in neuroscience research.
It is one of the fluids in closest contact with the central nervous system and thus, can be used …

Amyloid-β induces hepatic insulin resistance by activating JAK2/STAT3/SOCS-1 signaling pathway

Y Zhang, B Zhou, F Zhang, J Wu, Y Hu, Y Liu… - Diabetes, 2012 - Am Diabetes Assoc
Epidemiological studies indicate that patients with Alzheimer's disease (AD) have an
increased risk of developing type 2 diabetes mellitus (T2DM), and experimental studies …

Temporal course of cerebrospinal fluid dynamics and amyloid accumulation in the aging rat brain from three to thirty months

C Chiu, MC Miller, IN Caralopoulos, MS Worden… - Fluids and Barriers of …, 2012 - Springer
Background Amyloid accumulation in the brain parenchyma is a hallmark of Alzheimer's
disease (AD) and is seen in normal aging. Alterations in cerebrospinal fluid (CSF) dynamics …