[HTML][HTML] Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine
MS de Almeida, E Susnik, B Drasler… - Chemical society …, 2021 - pubs.rsc.org
Nanoparticles (NPs) have attracted considerable attention in various fields, such as
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …
[HTML][HTML] Recent advances in identifying protein targets in drug discovery
Phenotype-based screening has emerged as an alternative route for discovering new
chemical entities toward first-in-class therapeutics. However, clarifying their mode of action …
chemical entities toward first-in-class therapeutics. However, clarifying their mode of action …
[HTML][HTML] Fungal small RNAs ride in extracellular vesicles to enter plant cells through clathrin-mediated endocytosis
B He, H Wang, G Liu, A Chen, A Calvo, Q Cai… - Nature …, 2023 - nature.com
Small RNAs (sRNAs) of the fungal pathogen Botrytis cinerea can enter plant cells and hijack
host Argonaute protein 1 (AGO1) to silence host immunity genes. However, the mechanism …
host Argonaute protein 1 (AGO1) to silence host immunity genes. However, the mechanism …
Extracellular pectin-RALF phase separation mediates FERONIA global signaling function
Summary The FERONIA (FER)-LLG1 co-receptor and its peptide ligand RALF regulate
myriad processes for plant growth and survival. Focusing on signal-induced cell surface …
myriad processes for plant growth and survival. Focusing on signal-induced cell surface …
Insight into the role of clathrin‐mediated endocytosis inhibitors in SARS‐CoV‐2 infection
Emergence of SARS‐CoV‐2 variants warrants sustainable efforts to upgrade both the
diagnostic and therapeutic protocols. Understanding the details of cellular and molecular …
diagnostic and therapeutic protocols. Understanding the details of cellular and molecular …
Clathrin-mediated endocytosis facilitates the internalization of Magnaporthe oryzae effectors into rice cells
E Oliveira-Garcia, TM Tamang, J Park, M Dalby… - The Plant …, 2023 - academic.oup.com
Fungi and oomycetes deliver effectors into living plant cells to suppress defenses and
control plant processes needed for infection. Little is known about the mechanism by which …
control plant processes needed for infection. Little is known about the mechanism by which …
[HTML][HTML] The chemical inhibitors of endocytosis: from mechanisms to potential clinical applications
OK Szewczyk-Roszczenko, P Roszczenko… - Cells, 2023 - mdpi.com
Endocytosis is one of the major ways cells communicate with their environment. This
process is frequently hijacked by pathogens. Endocytosis also participates in the oncogenic …
process is frequently hijacked by pathogens. Endocytosis also participates in the oncogenic …
[HTML][HTML] Role of clathrin and dynamin in clathrin mediated endocytosis/synaptic vesicle recycling and implications in neurological diseases
KL Prichard, NS O'Brien, SR Murcia… - Frontiers in Cellular …, 2022 - frontiersin.org
Endocytosis is a process essential to the health and well-being of cell. It is required for the
internalisation and sorting of “cargo”—the macromolecules, proteins, receptors and lipids of …
internalisation and sorting of “cargo”—the macromolecules, proteins, receptors and lipids of …
[HTML][HTML] IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses
M Clement, JL Forbester, M Marsden… - Nature …, 2022 - nature.com
Interferon-induced transmembrane protein 3 (IFITM3) is a restriction factor that limits viral
pathogenesis and exerts poorly understood immunoregulatory functions. Here, using human …
pathogenesis and exerts poorly understood immunoregulatory functions. Here, using human …
Mass spectrometric exploration of phytohormone profiles and signaling networks
Phytohormones have crucial roles in plant growth, development, and acclimation to
environmental stress; however, measuring phytohormone levels and unraveling their …
environmental stress; however, measuring phytohormone levels and unraveling their …