The construct of frailty was first developed in gerontology to help identify older adults with
increased vulnerability when confronted with a health stressor. This article is a review of …

Clinical application of biomarkers is an integral component of transplant care. Clinicians and
scientists alike are in search of better biomarkers than the current serologic (serum …

Background: The kidney allograft biopsy is considered the gold standard for rejection
diagnosis but is invasive and could be indeterminate. Several publications point to the role …

Although the results of kidney transplantation (KT) have improved substantially in recent
years, a chronic and inexorable loss of grafts mainly due to the death of the patient and …

Antibody-mediated rejection (AMR) can cause graft failure following renal transplantation.
Neutrophils play a key role in AMR progression, but the exact mechanism remains unclear …

Kidney transplantation is the treatment of choice for patients with end-stage renal disease.
Although an improvement in graft survival has been observed in the last decades with the …

Biomarkers that could predict the evolution of the graft in transplanted patients and that
could allow to adapt the care of the patients would be an invaluable tool. Additionally …

Donor-derived cell-free DNA refers to the cell-free DNA derived from apoptosis or necrosis
of allograft tissue, circulating in the body fluids of patients after organ transplantation, and …

Uromodulin and microRNAs (miRNAs) have recently been investigated as potential
biomarkers for kidney graft associated pathology and outcome, with a special focus on …

Kidney transplantation is the preferred treatment for pediatric end-stage renal disease.
However, pediatric recipients face unique challenges due to their prolonged need for kidney …