Viruses numerically dominate our oceans; however, we have only just begun to document
the diversity, host range and infection dynamics of marine viruses, as well as the subsequent …

Metagenomics has changed the face of virus discovery by enabling the accurate
identification of viral genome sequences without requiring isolation of the viruses. As a …

Automated classification of CRISPR-Cas systems has been challenged by their dynamic
nature and expanding classification. Here, we developed CRISPRCasTyper, an automated …

Bacteria and archaea have evolved defense and regulatory mechanisms to cope with
various environmental stressors, including virus attack. This arsenal has been expanded by …

Bacteria have a range of distinct immune strategies that provide protection against
bacteriophage (phage) infections. While much has been learned about the mechanism of …

Many prokaryotes encode CRISPR-Cas systems as immune protection against mobile
genetic elements (MGEs), yet a number of MGEs also harbor CRISPR-Cas components …

Viral infections dynamically alter the composition and metabolic potential of marine
microbial communities and the evolutionary trajectories of host populations with resulting …

Viruses modulate microbial communities and alter ecosystem functions. However, due to
cultivation bottlenecks, specific virus–host interaction dynamics remain cryptic. In this study …

Viral metagenomics, or shotgun sequencing of purified viral particles, has revolutionized the
field of environmental virology by allowing the exploration of viral communities in a variety of …

Bacteria have been widely used as starter cultures in the food industry, notably for the
fermentation of milk into dairy products such as cheese and yogurt. Lactic acid bacteria used …