Organophosphate flame retardants in pregnant women: sources, occurrence, and potential risks to pregnancy outcomes

Y Li, X Wang, Q Zhu, Y Xu, Q Fu, T Wang… - Environmental …, 2023 - ACS Publications
Organophosphate flame retardants (OPFRs) are found in various environmental matrixes
and human samples. Exposure to OPFRs during gestation may interfere with pregnancy, for …

Occurrence, analysis and risk assessment of organophosphate esters (OPEs) in biota: A review

I Pantelaki, D Voutsa - Marine Pollution Bulletin, 2020 - Elsevier
Due to their widespread use, organophosphate esters (OPEs) are commonly detected in
various environmental matrices and have been identified as emerging contaminants. In this …

Occurrence, spatiotemporal distribution, and ecological risks of organophosphate esters in the water of the Yellow River to the Laizhou Bay, Bohai Sea

M Lian, C Lin, T Wu, M Xin, X Gu, S Lu, Y Cao… - Science of the Total …, 2021 - Elsevier
Limited information is available on the spatiotemporal occurrence and ecological risks of
organophosphate esters (OPEs) in coastal environments. 175 water samples were collected …

Cross-species applicability of an adverse outcome pathway network for thyroid hormone system disruption

AC Haigis, L Vergauwen, CA LaLone… - Toxicological …, 2023 - academic.oup.com
Thyroid hormone system disrupting compounds are considered potential threats for human
and environmental health. Multiple adverse outcome pathways (AOPs) for thyroid hormone …

[HTML][HTML] GAPS-megacities: A new global platform for investigating persistent organic pollutants and chemicals of emerging concern in urban air

A Saini, T Harner, S Chinnadhurai, JK Schuster… - Environmental …, 2020 - Elsevier
A pilot study was initiated in 2018 under the Global Atmospheric Passive Sampling (GAPS)
Network named GAPS-Megacities. This study included 20 megacities/major cities across the …

Thyroid Hormone Disruption by Organophosphate Esters Is Mediated by Nuclear/Membrane Thyroid Hormone Receptors: In Vitro, In Vivo, and In Silico Studies

J Li, Y Xu, N Li, R Zuo, Y Zhai… - Environmental Science & …, 2022 - ACS Publications
Earlier mechanistic studies of many prohibited flame retardants (FRs) highlighted their
thyroid hormone-disrupting activity through nuclear thyroid hormone receptors (nTRs) …

Prenatal exposure to triphenyl phosphate activated PPARγ in placental trophoblasts and impaired pregnancy outcomes

J Hong, M Jiang, L Guo, J Lin, Y Wang, H Tang… - Environmental …, 2022 - Elsevier
The health risks of triphenyl phosphate (TPhP) have increased since its widespread
application. Using placental trophoblast cell line JEG-3, we demonstrated that TPhP could …

Handwipes as indicators to assess organophosphate flame retardants exposure and thyroid hormone effects in e-waste dismantlers

J Tang, S Ma, X Hu, M Lin, G Li, Y Yu, T An - Journal of Hazardous Materials, 2023 - Elsevier
Dermal exposure is increasingly recognized as an important pathway for organic pollutant
exposure. However, data on dermal exposure are limited, particularly with respect to the …

Organophosphorus flame retardant induced hepatotoxicity and brain AChE inhibition on zebrafish (Danio rerio)

M Ramesh, S Angitha, S Haritha, RK Poopal… - Neurotoxicology and …, 2020 - Elsevier
Organophosphorus flame retardants (OPFRs) are high production volume (HPV) chemicals.
Recent reports reveal that OPFRs are ubiquitous in the environment. Unfortunately, the …

[HTML][HTML] Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP)

X Wang, F Li, J Liu, C Ji, H Wu - Ecotoxicology and environmental safety, 2020 - Elsevier
Triphenyl phosphate (TPP) has been found in various environmental media and in biota
suggesting widespread human exposure. However, there is still insufficient information on …