Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors
I Jurado-Martín, M Sainz-Mejías… - International journal of …, 2021 - mdpi.com
Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …
Role of Efflux Pumps on Antimicrobial Resistance in Pseudomonas aeruginosa
AB Lorusso, JA Carrara, CDN Barroso, FF Tuon… - International journal of …, 2022 - mdpi.com
Antimicrobial resistance is an old and silent pandemic. Resistant organisms emerge in
parallel with new antibiotics, leading to a major global public health crisis over time …
parallel with new antibiotics, leading to a major global public health crisis over time …
Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics
SJ Wood, TM Kuzel, SH Shafikhani - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …
causes many severe acute and chronic infections with high morbidity, and mortality rates as …
Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
Bacterial c-di-GMP has a key role in establishing host–microbe symbiosis
Most microbes evolve faster than their hosts and should therefore drive evolution of host–
microbe interactions. However, relatively little is known about the characteristics that define …
microbe interactions. However, relatively little is known about the characteristics that define …
The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
N Zhou, Y Jiang, TR Bergquist, AJ Lee, BZ Kacsoh… - Genome biology, 2019 - Springer
Abstract Background The Critical Assessment of Functional Annotation (CAFA) is an
ongoing, global, community-driven effort to evaluate and improve the computational …
ongoing, global, community-driven effort to evaluate and improve the computational …
Structure, function and regulation of Pseudomonas aeruginosa porins
S Chevalier, E Bouffartigues, J Bodilis… - FEMS microbiology …, 2017 - academic.oup.com
Pseudomonas aeruginosa is a Gram-negative bacterium belonging to the γ-proteobacteria.
Like other members of the Pseudomonas genus, it is known for its metabolic versatility and …
Like other members of the Pseudomonas genus, it is known for its metabolic versatility and …
The Pseudomonas aeruginosa Pan-Genome Provides New Insights on Its Population Structure, Horizontal Gene Transfer, and Pathogenicity
The huge increase in the availability of bacterial genomes led us to a point in which we can
investigate and query pan-genomes, for example, the full set of genes of a given bacterial …
investigate and query pan-genomes, for example, the full set of genes of a given bacterial …
A periplasmic phospholipase that maintains outer membrane lipid asymmetry in Pseudomonas aeruginosa
RL Guest, MJ Lee, W Wang… - Proceedings of the …, 2023 - National Acad Sciences
The outer membrane of Gram-negative bacteria is unique in both structure and function. The
surface-exposed outer leaflet is composed of lipopolysaccharide, while the inner leaflet is …
surface-exposed outer leaflet is composed of lipopolysaccharide, while the inner leaflet is …