Dried blood spot sampling in combination with LC‐MS/MS for quantitative analysis of small molecules

W Li, FLS Tse - Biomedical Chromatography, 2010 - Wiley Online Library
The collection of whole blood samples on paper, known as dried blood spot (DBS), dates
back to the early 1960s in newborn screening for inherited metabolic disorders. DBS offers a …

[HTML][HTML] Advantages and challenges of dried blood spot analysis by mass spectrometry across the total testing process

R Zakaria, KJ Allen, JJ Koplin, P Roche, RF Greaves - Ejifcc, 2016 - ncbi.nlm.nih.gov
Methods To address these aims we performed a key word search of the PubMed and
MEDLINE online databases in conjunction with individual manual searches to gather …

Adherence measurements in HIV: new advancements in pharmacologic methods and real-time monitoring

JR Castillo-Mancilla, JE Haberer - Current Hiv/aids Reports, 2018 - Springer
Abstract Purpose of Review In this review, we present new developments in antiretroviral
adherence, focusing on pharmacological measures and real-time adherence monitoring. In …

Emerging trends in paper spray mass spectrometry: Microsampling, storage, direct analysis, and applications

BS Frey, DE Damon… - Mass spectrometry …, 2020 - Wiley Online Library
Recent advancements in the sensitivity of chemical instrumentation have led to increased
interest in the use of microsamples for translational and biomedical research. Paper …

Dried blood spots: concepts, present status, and future perspectives in bioanalysis

A Sharma, S Jaiswal, M Shukla… - Drug testing and analysis, 2014 - Wiley Online Library
Over the past several years, dried blood spot (DBS) sampling technique has emerged as a
pertinent method in both qualitative and quantitative bioanalysis context. In the DBS method …

Use of dried blood spots in drug development: pharmacokinetic considerations

M Rowland, GT Emmons - The AAPS journal, 2010 - Springer
Dried blood spots are increasingly being used in drug development. This commentary
considers the pharmacokinetic issues that arise and compares these with those attached to …

[HTML][HTML] Pharmacokinetic considerations as to when to use dried blood spot sampling

G Emmons, M Rowland - Bioanalysis, 2010 - Taylor & Francis
In the past few years there has been a large increase in the reporting of the use of dried
blood spots (DBS) in drug development. Most of these reports pertain to the technological …

Procedures and practices for the validation of bioanalytical methods using dried blood spots: a review

NGL Jager, H Rosing, JHM Schellens, JH Beijnen - Bioanalysis, 2014 - Taylor & Francis
Dried blood spot (DBS) sampling, the collection of whole blood samples on paper, is an
emerging technique used for bioanalytical methods. Several analytical challenges, such as …

A LC–tandem MS assay for the simultaneous measurement of new antiretroviral agents: Raltegravir, maraviroc, darunavir, and etravirine

A Fayet, A Béguin, B Zanolari, S Cruchon… - … of Chromatography B, 2009 - Elsevier
Raltegravir (RAL), maraviroc (MVC), darunavir (DRV), and etravirine (ETV) are new
antiretroviral agents with significant potential for drug interactions. This work describes a …

HPLC–MS method for the quantification of nine anti-HIV drugs from dry plasma spot on glass filter and their long term stability in different conditions

A D'Avolio, M Simiele, M Siccardi, L Baietto… - … of pharmaceutical and …, 2010 - Elsevier
A bioanalytical method for the determination of most commonly prescribed protease
inhibitors (saquinavir, atazanavir, amprenavir, darunavir, lopinavir and ritonavir) and non …