Salt sensitivity and hypertension

O Balafa, RG Kalaitzidis - Journal of human hypertension, 2021 - nature.com
Salt sensitivity refers to the physiological trait present in mammals, including humans, by
which the blood pressure (BP) of some members of the population exhibits changes parallel …

Ouabain, endogenous ouabain and ouabain-like factors: The Na+ pump/ouabain receptor, its linkage to NCX, and its myriad functions

MP Blaustein, JM Hamlyn - Cell calcium, 2020 - Elsevier
In this brief review we discuss some aspects of the Na+ pump and its roles in mediating the
effects of ouabain and endogenous ouabain (EO): i) in regulating the cytosolic Ca 2+ …

The damaging duo: Obesity and excess dietary salt contribute to hypertension and cardiovascular disease

JC Watso, IS Fancher, DH Gomez… - Obesity …, 2023 - Wiley Online Library
Hypertension is a primary risk factor for cardiovascular disease. Cardiovascular disease is
the leading cause of death among adults worldwide. In this review, we focus on two of the …

[HTML][HTML] Mechanisms of dietary sodium-induced impairments in endothelial function and potential countermeasures

JC Patik, SL Lennon, WB Farquhar, DG Edwards - Nutrients, 2021 - mdpi.com
Despite decades of efforts to reduce sodium intake, excess dietary sodium remains
commonplace, and contributes to increased cardiovascular morbidity and mortality …

Short-term high-salt consumption does not influence resting or exercising heart rate variability but increases MCP-1 concentration in healthy young adults

BA Linder, MC Babcock, KU Pollin… - American Journal …, 2023 - journals.physiology.org
High salt consumption increases blood pressure (BP) and cardiovascular disease risk by
altering autonomic function and increasing inflammation. However, it is unclear whether salt …

[HTML][HTML] Dietary potassium attenuates the effects of dietary sodium on vascular function in salt-resistant adults

K Smiljanec, A Mbakwe, M Ramos Gonzalez… - Nutrients, 2020 - mdpi.com
The influence of dietary sodium and potassium on blood pressure (BP) has been extensively
studied, however their impact on endothelial function, particularly any interactive effects, has …

[HTML][HTML] A profile of SGLT-2 inhibitors in hyponatremia: The evidence to date

H Tang, C Xu, P Zhang, T Luo, Y Huang… - European Journal of …, 2023 - Elsevier
Hyponatremia is the most common electrolyte disorder in clinical practice, which may lead to
life-threatening complications. Several lines of evidence suggest that hyponatremia is …

Exploring heated exercise as a means of preventing the deleterious effects of high-sodium intake in Black women

SD Hunter, SA Kavouras… - American Journal of …, 2023 - journals.physiology.org
The purpose of this study was to examine whether hot yoga could attenuate sodium-induced
pressor responses and endothelial dysfunction in Black females. Fourteen participants …

[HTML][HTML] Tempol preserves endothelial progenitor cells in male mice with ambient fine particulate matter exposure

X Liu, A Wang, Z Chen, Y Cui, H Hao, TL Domeier… - Biomedicines, 2022 - mdpi.com
Ambient fine particulate matter (PM) exposure associates with an increased risk of
cardiovascular diseases (CVDs). Major sex differences between males and females exist in …

Salty Subjects: Unpacking Racial Differences in Salt-Sensitive Hypertension

S Jeong, SD Hunter, MD Cook, GJ Grosicki… - Current Hypertension …, 2024 - Springer
Abstract Purpose of Review To review underlying mechanisms and environmental factors
that may influence racial disparities in the development of salt-sensitive blood pressure …