The role of macrophage ion channels in the progression of atherosclerosis
Atherosclerosis is a complex inflammatory disease that affects the arteries and can lead to
severe complications such as heart attack and stroke. Macrophages, a type of immune cell …
severe complications such as heart attack and stroke. Macrophages, a type of immune cell …
The antidepressant paroxetine reduces the cardiac sodium current
IS Plijter, AO Verkerk, R Wilders - International journal of molecular …, 2023 - mdpi.com
A considerable amount of literature has been published on antidepressants and cardiac ion
channel dysfunction. The antidepressant paroxetine has been associated with Brugada …
channel dysfunction. The antidepressant paroxetine has been associated with Brugada …
Trp207 regulation of voltage-dependent activation of human Hv1 proton channel
In voltage-gated Na+ and K+ channels, the hydrophobicity of non-charged residues in the
S4 helix has been shown to regulate the S4 movement underlying the process of voltage …
S4 helix has been shown to regulate the S4 movement underlying the process of voltage …
Multitargeting in cardioprotection: An example of biaromatic compounds
GV Mokrov - Archiv der Pharmazie, 2023 - Wiley Online Library
A multitarget drug design approach is actively developing in modern medicinal chemistry
and pharmacology, especially with regard to multifactorial diseases such as cardiovascular …
and pharmacology, especially with regard to multifactorial diseases such as cardiovascular …