Reversal learning paradigms are among the most widely used tests of cognitive flexibility
and have been used as assays, across species, for altered cognitive processes in a host of …

In many circumstances alternative courses of action and thoughts have to be inhibited to
allow the emergence of goal-directed behavior. However, this has not been the accepted …

Successful goal-directed behavior requires not only correct action selection, planning, and
execution but also the ability to flexibly adapt behavior when performance problems occur or …

Evidence of marked variability in response among people exposed to the same
environmental risk implies that individual differences in genetic susceptibility might be at …

Regulating how fast to learn is critical for flexible behavior. Learning about the
consequences of actions should be slow in stable environments, but accelerate when that …

An increasingly popular method of assessing cognitive functions in rodents is the automated
touchscreen platform, on which a number of different cognitive tests can be run in a manner …

Serotonin is implicated in mood and affective disorders. However, growing evidence
suggests that a core endogenous role is to promote flexible adaptation to changes in the …

Addictions are often characterized as forms of impulsive behavior. That said, it is often noted
that impulsivity is a multidimensional construct, spanning several psychological domains …

Converging evidence indicates an association of the short (s), low-expressing variant of the
repeat length polymorphism, serotonin transporter-linked polymorphic region (5-HTTLPR) …

This protocol details a subset of assays developed within the touchscreen platform to
measure various aspects of executive function in rodents. Three main procedures are …