Recent aspects of the effects of zinc on human health
Zinc (Zn) is one of the most important essential nutrients of great public health significance. It
is involved in numerous biological functions and it is considered as a multipurpose trace …
is involved in numerous biological functions and it is considered as a multipurpose trace …
Zinc: from biological functions to therapeutic potential
MI Costa, AB Sarmento-Ribeiro… - International Journal of …, 2023 - mdpi.com
The trace element zinc (Zn) displays a wide range of biological functions. Zn ions control
intercellular communication and intracellular events that maintain normal physiological …
intercellular communication and intracellular events that maintain normal physiological …
Zinc deficiency and cellular oxidative stress: prognostic implications in cardiovascular diseases
Zinc is an essential nutrient for human health and has anti-oxidative stress and anti-
inflammatory functions. The association between zinc deficiency and the development of …
inflammatory functions. The association between zinc deficiency and the development of …
Physiological roles of zinc transporters: molecular and genetic importance in zinc homeostasis
T Hara, T Takeda, T Takagishi, K Fukue… - The Journal of …, 2017 - Springer
Zinc (Zn) is an essential trace mineral that regulates the expression and activation of
biological molecules such as transcription factors, enzymes, adapters, channels, and growth …
biological molecules such as transcription factors, enzymes, adapters, channels, and growth …
The functions of metallothionein and ZIP and ZnT transporters: an overview and perspective
T Kimura, T Kambe - International journal of molecular sciences, 2016 - mdpi.com
Around 3000 proteins are thought to bind zinc in vivo, which corresponds to~ 10% of the
human proteome. Zinc plays a pivotal role as a structural, catalytic, and signaling component …
human proteome. Zinc plays a pivotal role as a structural, catalytic, and signaling component …
Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension
Dysregulation of vascular stiffness and cellular metabolism occurs early in pulmonary
hypertension (PH). However, the mechanisms by which biophysical properties of the …
hypertension (PH). However, the mechanisms by which biophysical properties of the …
Roles of zinc signaling in the immune system
S Hojyo, T Fukada - Journal of immunology research, 2016 - Wiley Online Library
Zinc (Zn) is an essential micronutrient for basic cell activities such as cell growth,
differentiation, and survival. Zn deficiency depresses both innate and adaptive immune …
differentiation, and survival. Zn deficiency depresses both innate and adaptive immune …
The emerging role of zinc transporters in cellular homeostasis and cancer
E Bafaro, Y Liu, Y Xu, RE Dempski - Signal transduction and targeted …, 2017 - nature.com
Zinc is an essential micronutrient that plays a role in the structural or enzymatic functions of
many cellular proteins. Cellular zinc homeostasis involves the opposing action of two …
many cellular proteins. Cellular zinc homeostasis involves the opposing action of two …
Regulation of cell proliferation by hypoxia-inducible factors
ME Hubbi, GL Semenza - American Journal of Physiology …, 2015 - journals.physiology.org
Hypoxia is a physiological cue that impacts diverse physiological processes, including
energy metabolism, autophagy, cell motility, angiogenesis, and erythropoiesis. One of the …
energy metabolism, autophagy, cell motility, angiogenesis, and erythropoiesis. One of the …
The role of hypoxia-inducible factors in cardiovascular diseases
B Yu, X Wang, Y Song, G Xie, S Jiao, L Shi… - Pharmacology & …, 2022 - Elsevier
Cardiovascular diseases are the leading cause of death worldwide. During the development
of cardiovascular diseases, hypoxia plays a crucial role. Hypoxia-inducible factors (HIFs) are …
of cardiovascular diseases, hypoxia plays a crucial role. Hypoxia-inducible factors (HIFs) are …