The evolution of Ki-67 and breast carcinoma: past observations, present directions, and future considerations
BS Finkelman, H Zhang, DG Hicks, BM Turner - Cancers, 2023 - mdpi.com
Simple Summary Cellular proliferation is a central determinant of breast cancer recurrence
risk and response to chemotherapy. The discovery of the Ki-67 antibody by Dr. Johannes …
risk and response to chemotherapy. The discovery of the Ki-67 antibody by Dr. Johannes …
Paget's disease of the nipple
AC Sandoval-Leon, K Drews-Elger… - Breast cancer research …, 2013 - Springer
Paget's disease of the breast is a disorder of the nipple–areola complex that, while rare, is
often associated with an underlying carcinoma. It is characterized by eczematoid changes of …
often associated with an underlying carcinoma. It is characterized by eczematoid changes of …
Ki-67 can be used for further classification of triple negative breast cancer into two subtypes with different response and prognosis
Introduction Triple negative breast cancer (TNBC) has a poorer survival, despite a higher
response rate to neoadjuvant chemotherapy. The purpose of this study was to identify the …
response rate to neoadjuvant chemotherapy. The purpose of this study was to identify the …
Development of novel breast cancer recurrence prediction model using support vector machine
W Kim, KS Kim, JE Lee, DY Noh… - Journal of breast …, 2012 - synapse.koreamed.org
Purpose The prediction of breast cancer recurrence is a crucial factor for successful
treatment and follow-up planning. The principal objective of this study was to construct a …
treatment and follow-up planning. The principal objective of this study was to construct a …
PIK3CA Mutations May Be Discordant between Primary and Corresponding Metastatic Disease in Breast Cancer
J Dupont Jensen, AV Laenkholm, A Knoop… - Clinical Cancer …, 2011 - AACR
Purpose: PIK3CA mutations are frequent in breast cancer and activate the PI3K/Akt pathway.
Unexpectedly, PIK3CA mutation appears in general to be associated with better outcome. In …
Unexpectedly, PIK3CA mutation appears in general to be associated with better outcome. In …
Ki-67 as a predictor of response to neoadjuvant chemotherapy in breast cancer patients
KI Kim, KH Lee, TR Kim, YS Chun… - Journal of breast …, 2014 - synapse.koreamed.org
Purpose The objectives of this study were to assess the potential value of Ki-67 in predicting
response to neoadjuvant chemotherapy in breast cancer patients and to suggest a …
response to neoadjuvant chemotherapy in breast cancer patients and to suggest a …
Proliferative activity in hepatocellular carcinoma is closely correlated with glucose metabolism but not angiogenesis
BACKGROUND & AIMS: This study investigated the relationship between tumor proliferative
activity and the grade of tumor glucose metabolism or angiogenesis in hepatocellular …
activity and the grade of tumor glucose metabolism or angiogenesis in hepatocellular …
The Potential Utility of Curcumin in the Treatment of HER‐2‐Overexpressed Breast Cancer: An In Vitro and In Vivo Comparison Study with Herceptin
HW Lai, SY Chien, SJ Kuo, LM Tseng… - Evidence‐Based …, 2012 - Wiley Online Library
HER‐2 is an important oncoprotein overexpressed in about 15–25% of breast cancers. We
hypothesized that the ability of curcumin to downregulate HER‐2 oncoprotein and inhibit the …
hypothesized that the ability of curcumin to downregulate HER‐2 oncoprotein and inhibit the …
Proliferative activity in human breast cancer: Ki-67 automated evaluation and the influence of different Ki-67 equivalent antibodies
S Fasanella, E Leonardi, C Cantaloni, C Eccher… - Diagnostic …, 2011 - Springer
Abstract Background Ki67 labeling index (Ki67 LI), the percentage Ki67 immunoreactive
cells, is a measure of tumor proliferation, with important clinical relevance in breast cancer …
cells, is a measure of tumor proliferation, with important clinical relevance in breast cancer …
Ki-67 and breast cancer prognosis: does it matter if Ki-67 level is examined using preoperative biopsy or postoperative specimen?
SB Choi, JM Park, JH Ahn, J Go, J Kim, HS Park… - Breast Cancer Research …, 2022 - Springer
Purpose This study aimed to identify the association between Ki-67 level and the prognosis
of patients with breast cancer, regardless of the timing of Ki-67 testing (using preoperative …
of patients with breast cancer, regardless of the timing of Ki-67 testing (using preoperative …