Current advance of nanotechnology in diagnosis and treatment for malignant tumors
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
[HTML][HTML] Functionalized liposomes for targeted breast cancer drug delivery
Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …
treatment strategies, it remains a prominent cause of female mortality worldwide …
Colorectal Tumor Microenvironment‐Activated Bio‐Decomposable and Metabolizable Cu2O@CaCO3 Nanocomposites for Synergistic Oncotherapy
Rational design of tumor microenvironment (TME)‐activated nanocomposites provides an
innovative strategy to construct responsive oncotherapy. In colorectal cancer (CRC), the …
innovative strategy to construct responsive oncotherapy. In colorectal cancer (CRC), the …
Eph receptors and ephrins in cancer progression
EB Pasquale - Nature Reviews Cancer, 2024 - nature.com
Evidence implicating Eph receptor tyrosine kinases and their ephrin ligands (that together
make up the 'Eph system') in cancer development and progression has been accumulating …
make up the 'Eph system') in cancer development and progression has been accumulating …
Lipid nanoparticles functionalized with antibodies for anticancer drug therapy
AC Marques, PC Costa, S Velho, MH Amaral - Pharmaceutics, 2023 - mdpi.com
Nanotechnology takes the lead in providing new therapeutic options for cancer patients. In
the last decades, lipid-based nanoparticles—solid lipid nanoparticles (SLNs) …
the last decades, lipid-based nanoparticles—solid lipid nanoparticles (SLNs) …
Docetaxel: An update on its molecular mechanisms, therapeutic trajectory and nanotechnology in the treatment of breast, lung and prostate cancer
Amongst the various microtubule-targeting agents, Docetaxel (DTX) has gained immense
attention in cancer chemotherapy due to its good therapeutic index. DTX belongs to the …
attention in cancer chemotherapy due to its good therapeutic index. DTX belongs to the …
Challenges of current anticancer treatment approaches with focus on liposomal drug delivery systems
V Gyanani, JC Haley, R Goswami - Pharmaceuticals, 2021 - mdpi.com
According to a 2020 World Health Organization report (Globocan 2020), cancer was a
leading cause of death worldwide, accounting for nearly 10 million deaths in 2020. The aim …
leading cause of death worldwide, accounting for nearly 10 million deaths in 2020. The aim …
MMAE Delivery Using the Bicycle Toxin Conjugate BT5528
G Bennett, A Brown, G Mudd, P Huxley… - Molecular Cancer …, 2020 - AACR
The EphA2 receptor is found at high levels in tumors and low levels in normal tissue and
high EphA2 expression in biopsies is a predictor of poor outcome in patients. Drug discovery …
high EphA2 expression in biopsies is a predictor of poor outcome in patients. Drug discovery …
When liposomes met antibodies: Drug delivery and beyond
Drug encapsulated liposomes and monoclonal antibodies (Mabs) are two distinctively
different classes of therapeutics, but both aim to become the ultimate “magic bullet”. While …
different classes of therapeutics, but both aim to become the ultimate “magic bullet”. While …
Controlled intracellular polymerization for cancer treatment
Numerous prodrugs have been developed and used for cancer treatments to reduce side
effects and promote efficacy. In this work, we have developed a new photoactivatable …
effects and promote efficacy. In this work, we have developed a new photoactivatable …