Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

[HTML][HTML] Functionalized liposomes for targeted breast cancer drug delivery

J Nel, K Elkhoury, É Velot, A Bianchi, S Acherar… - Bioactive materials, 2023 - Elsevier
Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …

Colorectal Tumor Microenvironment‐Activated Bio‐Decomposable and Metabolizable Cu2O@CaCO3 Nanocomposites for Synergistic Oncotherapy

M Chang, Z Hou, D Jin, J Zhou, M Wang… - Advanced …, 2020 - Wiley Online Library
Rational design of tumor microenvironment (TME)‐activated nanocomposites provides an
innovative strategy to construct responsive oncotherapy. In colorectal cancer (CRC), the …

Eph receptors and ephrins in cancer progression

EB Pasquale - Nature Reviews Cancer, 2024 - nature.com
Evidence implicating Eph receptor tyrosine kinases and their ephrin ligands (that together
make up the 'Eph system') in cancer development and progression has been accumulating …

Lipid nanoparticles functionalized with antibodies for anticancer drug therapy

AC Marques, PC Costa, S Velho, MH Amaral - Pharmaceutics, 2023 - mdpi.com
Nanotechnology takes the lead in providing new therapeutic options for cancer patients. In
the last decades, lipid-based nanoparticles—solid lipid nanoparticles (SLNs) …

Docetaxel: An update on its molecular mechanisms, therapeutic trajectory and nanotechnology in the treatment of breast, lung and prostate cancer

M Imran, S Saleem, A Chaudhuri, J Ali… - Journal of Drug Delivery …, 2020 - Elsevier
Amongst the various microtubule-targeting agents, Docetaxel (DTX) has gained immense
attention in cancer chemotherapy due to its good therapeutic index. DTX belongs to the …

Challenges of current anticancer treatment approaches with focus on liposomal drug delivery systems

V Gyanani, JC Haley, R Goswami - Pharmaceuticals, 2021 - mdpi.com
According to a 2020 World Health Organization report (Globocan 2020), cancer was a
leading cause of death worldwide, accounting for nearly 10 million deaths in 2020. The aim …

MMAE Delivery Using the Bicycle Toxin Conjugate BT5528

G Bennett, A Brown, G Mudd, P Huxley… - Molecular Cancer …, 2020 - AACR
The EphA2 receptor is found at high levels in tumors and low levels in normal tissue and
high EphA2 expression in biopsies is a predictor of poor outcome in patients. Drug discovery …

When liposomes met antibodies: Drug delivery and beyond

J Di, F Xie, Y Xu - Advanced Drug Delivery Reviews, 2020 - Elsevier
Drug encapsulated liposomes and monoclonal antibodies (Mabs) are two distinctively
different classes of therapeutics, but both aim to become the ultimate “magic bullet”. While …

Controlled intracellular polymerization for cancer treatment

Y Zhang, Q Gao, W Li, R He, L Zhu, Q Lian, L Wang… - JACS Au, 2022 - ACS Publications
Numerous prodrugs have been developed and used for cancer treatments to reduce side
effects and promote efficacy. In this work, we have developed a new photoactivatable …