Evolving concepts of the vulnerable atherosclerotic plaque and the vulnerable patient: implications for patient care and future research

P Gaba, BJ Gersh, J Muller, J Narula… - Nature Reviews …, 2023 - nature.com
Understanding the natural history of coronary artery atherosclerosis is necessary to
determine prognosis and prescribe effective therapies. Traditional management of coronary …

Glycocalyx in atherosclerosis-relevant endothelium function and as a therapeutic target

R Mitra, GL O'Neil, IC Harding, MJ Cheng… - Current atherosclerosis …, 2017 - Springer
Abstract Purpose of Review The cell surface-attached extracellular glycocalyx (GCX) layer is
a major contributor to endothelial cell (EC) function and EC-dependent vascular health and …

Intracranial plaque enhancement in patients with cerebrovascular events on high-spatial-resolution MR images

Y Qiao, SR Zeiler, S Mirbagheri, R Leigh, V Urrutia… - Radiology, 2014 - pubs.rsna.org
Purpose To characterize intracranial plaque inflammation in vivo by using three-dimensional
(3D) high-spatial-resolution contrast material–enhanced black-blood (BB) magnetic …

Noninvasive magnetic resonance imaging evaluation of endothelial permeability in murine atherosclerosis using an albumin-binding contrast agent

A Phinikaridou, ME Andia, A Protti, A Indermuehle… - Circulation, 2012 - Am Heart Assoc
Background—Endothelial dysfunction promotes atherosclerosis and precedes acute
cardiovascular events. We investigated whether in vivo magnetic resonance imaging with …

Porphyromonas gingivalis accelerates inflammatory atherosclerosis in the innominate artery of ApoE deficient mice

C Hayashi, J Viereck, N Hua, A Phinikaridou… - Atherosclerosis, 2011 - Elsevier
OBJECTIVE: Studies in humans support a role for the oral pathogen Porphyromonas
gingivalis in the development of inflammatory atherosclerosis. The goal of this study was to …

Recent advances in molecular imaging of atherosclerotic plaques and thrombosis

R Qiao, X Huang, Y Qin, Y Li, TP Davis, CE Hagemeyer… - Nanoscale, 2020 - pubs.rsc.org
As the complications of atherosclerosis such as myocardial infarction and stroke are still one
of the leading causes of mortality worldwide, the development of new diagnostic tools for the …

Dextran sulfate-coated superparamagnetic iron oxide nanoparticles as a contrast agent for atherosclerosis imaging

DG You, G Saravanakumar, S Son, HS Han, R Heo… - Carbohydrate …, 2014 - Elsevier
The hallmark of atherosclerosis in its early pathogenic process is the overexpression of
class A scavenger receptors (SR-A) by activated macrophages. In this study, dextran sulfate …

Atherosclerosis, periodontal disease, and treatment with resolvins

JA Hamilton, H Hasturk, A Kantarci, CN Serhan… - Current atherosclerosis …, 2017 - Springer
Abstract Purpose of Review This review aims to discuss the existing evidence on the link
between atherosclerosis and periodontitis by particularly presenting new findings that link …

Effects of colchicine on atherosclerotic plaque stabilization: a multimodality imaging study in an animal model

A Cecconi, JP Vilchez-Tschischke, J Mateo… - Journal of …, 2021 - Springer
Colchicine demonstrated clinical benefits in the treatment of stable coronary artery disease.
Our aim was to evaluate the effects of colchicine on atherosclerotic plaque stabilization …

Three-dimensional imaging provides detailed atherosclerotic plaque morphology and reveals angiogenesis after carotid artery ligation

T Becher, DF Riascos-Bernal, DJ Kramer… - Circulation …, 2020 - Am Heart Assoc
Rationale: Remodeling of the vessel wall and the formation of vascular networks are
dynamic processes that occur during mammalian embryonic development and in adulthood …