The ROSMAP project: aging and neurodegenerative diseases through omic sciences
AP Pérez-González, AL García-Kroepfly… - Frontiers in …, 2024 - frontiersin.org
The Religious Order Study and Memory and Aging Project (ROSMAP) is an initiative that
integrates two longitudinal cohort studies, which have been collecting clinicopathological …
integrates two longitudinal cohort studies, which have been collecting clinicopathological …
[PDF][PDF] Integrative proteomics identifies a conserved Ab amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer's disease
T Ladd, F Afroz, T Islam, J Jagirdar, CC Funk… - Cell …, 2024 - researchgate.net
Alzheimer's disease (AD) is a complex neurodegenerative disorder that develops over
decades. AD brain proteomics reveals vast alterations in protein levels and numerous …
decades. AD brain proteomics reveals vast alterations in protein levels and numerous …
An analysis of RNA quality metrics in human brain tissue
J Tian, TG Lam, SK Ross, B Ciener… - … of Neuropathology & …, 2024 - academic.oup.com
Human brain tissue studies have used a range of metrics to assess RNA quality but there
are few large-scale cross-comparisons of presequencing quality metrics with RNA-seq …
are few large-scale cross-comparisons of presequencing quality metrics with RNA-seq …
Transcriptome-wide association study of Alzheimer disease reveals many differentially expressed genes and multiple biological pathways in brain tissue from African …
Background: The genetic basis of Alzheimer disease (AD) in African American (AA)
individuals is much less well understood than in European-ancestry (EA) individuals …
individuals is much less well understood than in European-ancestry (EA) individuals …
Integrative proteomics identifies a conserved Aβ amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer's disease
Alzheimer's disease (AD) is a complex neurodegenerative disorder that develops over
decades. AD brain proteomics reveals vast alterations in protein levels and numerous …
decades. AD brain proteomics reveals vast alterations in protein levels and numerous …
[HTML][HTML] Large-scale Deep Proteomic Analysis in Alzheimer's Disease Brain Regions Across Race and Ethnicity
Methods Dorsolateral prefrontal cortex (DLPFC) and superior temporal gyrus (STG) brain
tissues were donated from multiple centers (Mayo Clinic, Emory University, Rush University …
tissues were donated from multiple centers (Mayo Clinic, Emory University, Rush University …
Nomination of a novel plasma protein biomarker panel capable of classifying Alzheimer's disease dementia with high accuracy in an African American cohort
LA Kuchenbecker, KJ Thompson, CD Hurst… - …, 2024 - pmc.ncbi.nlm.nih.gov
Introduction: African Americans (AA) are widely underrepresented in plasma biomarker
studies for Alzheimer's disease (AD) and current diagnostic biomarker candidates do not …
studies for Alzheimer's disease (AD) and current diagnostic biomarker candidates do not …