[HTML][HTML] IL-1R8: A molecular brake of anti-tumor and anti-viral activity of NK cells and ILC

FR Mariotti, D Supino, N Landolina, C Garlanda… - Seminars in …, 2023 - Elsevier
Interleukin-1 receptor family members (ILRs) and Toll-Like Receptors (TLRs) play pivotal
role in immunity and inflammation and are expressed by most cell types including cells of …

Negative regulation of the IL-1 system by IL-1R2 and IL-1R8: Relevance in pathophysiology and disease

D Supino, L Minute, A Mariancini, F Riva… - Frontiers in …, 2022 - frontiersin.org
Interleukin-1 (IL-1) is a primary cytokine of innate immunity and inflammation. IL-1 belongs to
a complex family including ligands with agonist activity, receptor antagonists, and an anti …

[HTML][HTML] Genome-wide association study of anogenital distance and its (co) variances with fertility in growing and lactating Holstein-Friesian dairy cattle

MA Stephen, CR Burke, N Steele, JE Pryce… - Journal of Dairy …, 2023 - Elsevier
Anogenital distance (AGD) is a moderately heritable trait that can be measured at a young
age that may provide an opportunity to indirectly select for improved fertility in dairy cattle. In …

Identification of copy number variations and genetic diversity in Italian insular sheep breeds

R Di Gerlando, S Mastrangelo, M Tolone, I Rizzuto… - Animals, 2022 - mdpi.com
Simple Summary The aim of this work is to identify CNVs and perform a CNV-based
population genetics analysis in five Italian sheep breeds (Barbaresca, Comisana, Pinzirita …

In-depth systems biological evaluation of bovine alveolar macrophages suggests novel insights into molecular mechanisms underlying Mycobacterium bovis infection

A Hasankhani, A Bahrami, S Mackie… - Frontiers in …, 2022 - frontiersin.org
Objective Bovine tuberculosis (bTB) is a chronic respiratory infectious disease of domestic
livestock caused by intracellular Mycobacterium bovis infection, which causes~ $3 billion in …

Runs of homocigosity and its association with productive traits in Mexican Holstein cattle

JG Cortes-Hernández, FJ Ruiz-López… - PLoS …, 2022 - journals.plos.org
The objective of this study was to describe the runs of homozygosity (ROH) detected in the
Mexican Holstein population and to associate them with milk, fat and protein yields, and …

Genome-Wide Association Study Reveals Quantitative Trait Loci and Candidate Genes Associated with High Interferon-gamma Production in Holstein Cattle Naturally …

G Badia-Bringué, M Canive, P Vázquez… - International Journal of …, 2024 - mdpi.com
Mycobacterium bovis (Mb) is the causative agent of bovine tuberculosis (bTb). Genetic
selection aiming to identify less susceptible animals has been proposed as a …

Cis-eQTL analysis reveals genes involved in biological processes of the immune system in Nelore cattle

TCF Dos Santos, EN Silva, GB Frezarim, BM Salatta… - Gene, 2025 - Elsevier
The combination of transcriptional profiling and genotype data analyses enables the
identification of genetic variants that may affect gene expression (eQTL–expression …

Whole‐genome resequencing deciphers patterns of genetic diversity, phylogeny, and evolutionary dynamics in Kashmir cattle

Z Ahmed, W Xiang, F Wang, M Nawaz… - Animal …, 2024 - Wiley Online Library
Kashmir cattle, which were kept by local pastoralists for centuries, are exceptionally resilient
and adaptive to harsh environments. Despite its significance, the genomic characteristics of …

Cathepsin S Is More Abundant in Serum of Mycobacterium avium subsp. paratuberculosis-Infected Dairy Cows

HC Duda, C von Toerne, L Korbonits, A Didier… - Metabolites, 2024 - mdpi.com
Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of bovine
paratuberculosis, a chronic granulomatous enteritis leading to economic losses and posing …