Here, there, and everywhere: The importance of ER membrane contact sites
H Wu, P Carvalho, GK Voeltz - Science, 2018 - science.org
BACKGROUND The defining feature of eukaryotic cells is the presence of membrane-bound
organelles of diverse kinds, each with specialized functions. Most organelles have multiple …
organelles of diverse kinds, each with specialized functions. Most organelles have multiple …
SERCA control of cell death and survival
ER Chemaly, L Troncone, D Lebeche - Cell calcium, 2018 - Elsevier
Abstract Intracellular calcium (Ca 2+) is a critical coordinator of various aspects of cellular
physiology. It is increasingly apparent that changes in cellular Ca 2+ dynamics contribute to …
physiology. It is increasingly apparent that changes in cellular Ca 2+ dynamics contribute to …
Dysregulation of mitochondrial Ca2+ uptake and sarcolemma repair underlie muscle weakness and wasting in patients and mice lacking MICU1
Muscle function is regulated by Ca 2+, which mediates excitation-contraction coupling,
energy metabolism, adaptation to exercise, and sarcolemmal repair. Several of these …
energy metabolism, adaptation to exercise, and sarcolemmal repair. Several of these …
Prepubertal skeletal muscle growth requires Pax7-expressing satellite cell-derived myonuclear contribution
The functional role of Pax7-expressing satellite cells (SCs) in postnatal skeletal muscle
development beyond weaning remains obscure. Therefore, the relevance of SCs during …
development beyond weaning remains obscure. Therefore, the relevance of SCs during …
Calcium regulation of bacterial virulence
Abstract Calcium (Ca 2+) is a universal signaling ion, whose major informational role
shaped the evolution of signaling pathways, enabling cellular communications and …
shaped the evolution of signaling pathways, enabling cellular communications and …
Calreticulin: Endoplasmic reticulum Ca2+ gatekeeper
M Michalak - Journal of Cellular and Molecular Medicine, 2024 - Wiley Online Library
Endoplasmic reticulum (ER) luminal Ca2+ is vital for the function of the ER and regulates
many cellular processes. Calreticulin is a highly conserved, ER‐resident Ca2+ binding …
many cellular processes. Calreticulin is a highly conserved, ER‐resident Ca2+ binding …
Calcium dynamics mediated by the endoplasmic/sarcoplasmic reticulum and related diseases
FN Reddish, CL Miller, R Gorkhali, JJ Yang - International journal of …, 2017 - mdpi.com
The flow of intracellular calcium (Ca2+) is critical for the activation and regulation of
important biological events that are required in living organisms. As the major Ca2+ …
important biological events that are required in living organisms. As the major Ca2+ …
[HTML][HTML] Focused ultrasound activates voltage-gated calcium channels through depolarizing TRPC1 sodium currents in kidney and skeletal muscle
Pulsed focused ultrasound (pFUS) technology is being developed for clinical neuro/immune
modulation and regenerative medicine. Biological signal transduction of pFUS forces can …
modulation and regenerative medicine. Biological signal transduction of pFUS forces can …
Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challenge
MB Elam, G Majumdar, K Mozhui, IC Gerling, SR Vera… - PLoS …, 2017 - journals.plos.org
Statins, the 3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase inhibitors, are widely
prescribed for treatment of hypercholesterolemia. Although statins are generally well …
prescribed for treatment of hypercholesterolemia. Although statins are generally well …
[HTML][HTML] The relevance of organelle interactions in cellular senescence
J Huang, P Meng, C Wang, Y Zhang, L Zhou - Theranostics, 2022 - ncbi.nlm.nih.gov
Organelles are tiny structures with specific functions in eukaryotic cells. Since they are
covered with membranes, different organelles can perform biological processes that are …
covered with membranes, different organelles can perform biological processes that are …